|
Atomistry » Chlorine » PDB 2yc5-2yj8 » 2yek | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2yc5-2yj8 » 2yek » |
Chlorine in PDB 2yek: Crystal Structure of the First Bromodomain of Human BRD2 with the Inhibitor GSK525762 (Ibet)Protein crystallography data
The structure of Crystal Structure of the First Bromodomain of Human BRD2 with the Inhibitor GSK525762 (Ibet), PDB code: 2yek
was solved by
C.W.Chung,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the First Bromodomain of Human BRD2 with the Inhibitor GSK525762 (Ibet)
(pdb code 2yek). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of the First Bromodomain of Human BRD2 with the Inhibitor GSK525762 (Ibet), PDB code: 2yek: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 2yekGo back to Chlorine Binding Sites List in 2yek
Chlorine binding site 1 out
of 3 in the Crystal Structure of the First Bromodomain of Human BRD2 with the Inhibitor GSK525762 (Ibet)
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 2yekGo back to Chlorine Binding Sites List in 2yek
Chlorine binding site 2 out
of 3 in the Crystal Structure of the First Bromodomain of Human BRD2 with the Inhibitor GSK525762 (Ibet)
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 2yekGo back to Chlorine Binding Sites List in 2yek
Chlorine binding site 3 out
of 3 in the Crystal Structure of the First Bromodomain of Human BRD2 with the Inhibitor GSK525762 (Ibet)
Mono view Stereo pair view
Reference:
C.W.Chung,
H.Coste,
J.H.White,
O.Mirguet,
J.Wilde,
R.L.Gosmini,
C.Delves,
S.M.Magny,
R.Woodward,
S.A.Hughes,
E.V.Boursier,
H.Flynn,
A.M.Bouillot,
P.Bamborough,
J.M.Brusq,
F.J.Gellibert,
E.J.Jones,
A.M.Riou,
P.Homes,
S.L.Martin,
I.J.Uings,
J.Toum,
C.A.Clement,
A.B.Boullay,
R.L.Grimley,
F.M.Blandel,
R.K.Prinjha,
K.Lee,
J.Kirilovsky,
E.Nicodeme.
Discovery and Characterization of Small Molecule Inhibitors of the Bet Family Bromodomains. J.Med.Chem. V. 54 3827 2011.
Page generated: Sat Dec 12 09:28:47 2020
ISSN: ISSN 0022-2623 PubMed: 21568322 DOI: 10.1021/JM200108T |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |