Chlorine in PDB 2z9x: Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine

All present enzymatic activity of Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine:
2.6.1.30;

The structure of Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine, PDB code: 2z9x was solved by Y.Yoshikane, N.Yokochi, M.Yamasaki, K.Mizutani, K.Ohnishi, B.Mikami, H.Hayashi, T.Yagi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.92 / 1.94
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	68.720, 68.720, 311.942, 90.00, 90.00, 90.00
R / Rfree (%)	14.5 / 18.4

The binding sites of Chlorine atom in the Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine (pdb code 2z9x). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine, PDB code: 2z9x:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1608 b:21.6 occ:1.00 O A:HOH1741 3.2 21.9 1.0 NZ A:LYS197 3.2 22.5 1.0 N A:ASN196 3.2 17.3 1.0 CG A:PRO69 3.6 14.1 1.0 O A:HOH1708 3.6 28.1 1.0 CD A:PRO69 3.6 14.2 1.0 CD A:LYS197 3.7 21.1 1.0 C A:GLY194 3.7 17.7 1.0 N A:PRO195 3.7 18.5 1.0 CB A:ASN196 3.7 18.4 1.0 CA A:GLY194 3.7 16.5 1.0 CA A:ASN196 3.8 17.7 1.0 CD A:PRO195 3.8 19.0 1.0 CE A:LYS197 4.0 22.3 1.0 C A:ASN196 4.1 17.6 1.0 C A:PRO195 4.3 17.8 1.0 O A:HOH1720 4.3 20.8 1.0 O A:GLY194 4.3 17.7 1.0 N A:LYS197 4.4 17.4 1.0 CG1 A:VAL173 4.4 12.6 1.0 CA A:PRO195 4.5 18.5 1.0 N A:GLY194 4.6 15.9 1.0 O A:LEU205 4.6 14.3 1.0 O A:ASN196 4.7 17.8 1.0 CG A:PRO195 4.8 19.1 1.0 OP4 A:PXL1503 4.8 16.0 1.0 OE2 A:GLU68 4.9 15.6 1.0 CB A:PRO69 4.9 13.3 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase Complexed with Pyridoxyl-L-Alanine within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2608 b:18.3 occ:1.00 O B:HOH2665 2.9 19.2 1.0 NZ B:LYS197 3.2 13.5 1.0 N B:ASN196 3.2 15.4 1.0 CD B:PRO195 3.5 16.2 1.0 CG B:PRO69 3.5 12.7 1.0 CD B:PRO69 3.6 12.8 1.0 N B:PRO195 3.6 16.1 1.0 C B:GLY194 3.6 15.5 1.0 CA B:GLY194 3.7 14.8 1.0 CD B:LYS197 3.7 14.1 1.0 CB B:ASN196 3.8 16.5 1.0 CA B:ASN196 3.9 15.8 1.0 O B:HOH2712 4.0 20.5 1.0 CE B:LYS197 4.0 15.2 1.0 CG B:PRO195 4.2 16.7 1.0 C B:PRO195 4.2 15.7 1.0 C B:ASN196 4.2 15.4 1.0 O B:HOH2691 4.3 17.3 1.0 O B:GLY194 4.3 15.3 1.0 CG1 B:VAL173 4.4 10.9 1.0 CA B:PRO195 4.4 16.4 1.0 O B:LEU205 4.4 13.8 1.0 N B:LYS197 4.5 14.6 1.0 N B:GLY194 4.5 14.6 1.0 OP4 B:PXL2503 4.8 15.8 1.0 O B:ASN196 4.8 15.3 1.0 CB B:PRO69 4.9 11.8 1.0 OE2 B:GLU68 4.9 15.3 1.0

Y.Yoshikane, N.Yokochi, M.Yamasaki, K.Mizutani, K.Ohnishi, B.Mikami, H.Hayashi, T.Yagi. Crystal Structure of Pyridoxamine-Pyruvate Aminotransferase From Mesorhizobium Loti MAFF303099 J.Biol.Chem. V. 283 1120 2008.
ISSN: ISSN 0021-9258
PubMed: 17989071
DOI: 10.1074/JBC.M708061200