Chlorine in PDB 2zhp: Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative

The structure of Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative, PDB code: 2zhp was solved by H.Okumura, I.Miyazaki, S.Simizu, H.Osada, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.11 / 1.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	39.992, 53.868, 125.498, 90.00, 90.00, 90.00
R / Rfree (%)	18.7 / 21.6

The structure of Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative also contains other interesting chemical elements:

Copper

(Cu)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative (pdb code 2zhp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative, PDB code: 2zhp:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:19.6 occ:1.00 OH3 A:BY6301 3.1 13.2 1.0 NL A:BY6301 3.3 7.2 1.0 NK A:BY6301 3.3 8.8 1.0 NG A:BY6301 3.4 6.6 1.0 NE2 A:HIS117 3.5 13.1 1.0 C33 A:BY6301 3.5 10.1 1.0 C38 A:BY6301 3.5 8.4 1.0 C10 A:BY6301 3.7 6.6 1.0 CD2 A:LEU63 3.7 17.1 1.0 CU A:CU302 3.7 12.9 1.0 NH A:BY6301 3.8 10.3 1.0 C7 A:BY6301 3.8 9.4 1.0 SG A:CYS115 3.8 13.3 1.0 C31 A:BY6301 3.8 8.4 1.0 C12 A:BY6301 3.9 8.4 1.0 C34 A:BY6301 4.0 8.0 1.0 CE1 A:HIS117 4.0 10.4 1.0 C37 A:BY6301 4.0 8.2 1.0 CB A:BY6301 4.1 9.4 1.0 C6 A:BY6301 4.2 10.8 1.0 C36 A:BY6301 4.2 10.8 1.0 CB A:CYS115 4.2 9.1 1.0 NJ A:BY6301 4.3 5.5 1.0 C30 A:BY6301 4.3 9.6 1.0 NE A:BY6301 4.5 7.9 1.0 C9 A:BY6301 4.5 7.4 1.0 C29 A:BY6301 4.6 11.2 1.0 OH2 A:BY6301 4.6 12.9 1.0 O40 A:BY6301 4.6 11.8 1.0 CD2 A:HIS117 4.7 8.2 1.0 NC A:BY6301 4.7 10.8 1.0 C13 A:BY6301 4.7 9.8 1.0 O12 A:BY6301 4.8 9.7 1.0 C40 A:BY6301 4.8 7.0 1.0 C8 A:BY6301 4.8 9.0 1.0 CD1 A:LEU63 4.9 14.7 1.0 CG A:LEU63 4.9 10.1 1.0 CD A:BY6301 4.9 10.6 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:25.8 occ:1.00 NL B:BY6401 3.2 15.2 1.0 NG B:BY6401 3.2 8.4 1.0 NK B:BY6401 3.2 16.1 1.0 OH3 B:BY6401 3.3 20.6 1.0 C33 B:BY6401 3.4 20.8 1.0 CU B:CU402 3.5 17.1 1.0 C38 B:BY6401 3.6 16.9 1.0 C10 B:BY6401 3.6 13.3 1.0 C7 B:BY6401 3.6 13.4 1.0 NH B:BY6401 3.7 18.6 1.0 C31 B:BY6401 3.8 21.3 1.0 CD2 B:LEU63 3.8 13.6 1.0 NE2 B:HIS117 3.8 15.4 1.0 C12 B:BY6401 3.9 16.6 1.0 C34 B:BY6401 3.9 21.6 1.0 C6 B:BY6401 4.0 12.2 1.0 C37 B:BY6401 4.0 16.9 1.0 C36 B:BY6401 4.1 20.6 1.0 SG B:CYS115 4.1 14.0 1.0 NJ B:BY6401 4.1 24.6 1.0 CB B:BY6401 4.1 22.1 1.0 C30 B:BY6401 4.2 21.1 1.0 CE1 B:HIS117 4.3 14.6 1.0 NE B:BY6401 4.4 8.8 1.0 O40 B:BY6401 4.5 17.7 1.0 NC B:BY6401 4.5 14.0 1.0 C29 B:BY6401 4.5 21.5 1.0 C9 B:BY6401 4.5 11.1 1.0 OH2 B:BY6401 4.5 23.7 1.0 C13 B:BY6401 4.6 20.8 1.0 CB B:CYS115 4.6 8.1 1.0 C40 B:BY6401 4.7 13.1 1.0 O12 B:BY6401 4.8 18.2 1.0 C8 B:BY6401 4.8 9.4 1.0 C27 B:BY6401 4.9 25.6 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Bleomycin-Binding Protein From Streptoalloteichus Hindustanus Complexed with Bleomycin Derivative within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl404 b:10.7 occ:1.00 OD2 B:ASP25 2.0 19.6 1.0 OE2 B:GLU21 2.1 27.6 1.0 CD B:GLU21 2.6 20.8 1.0 OE1 B:GLU21 2.6 23.9 1.0 CG B:ASP25 3.0 15.1 1.0 CB B:ASP25 3.4 9.1 1.0 O B:HOH609 3.9 28.9 1.0 CG B:GLU21 4.0 21.2 1.0 OD1 B:ASP25 4.1 13.4 1.0 O B:GLU21 4.8 9.2 1.0 CA B:ASP25 4.9 8.4 1.0 CB B:GLU21 5.0 10.0 1.0

I.Miyazaki, H.Okumura, S.Simizu, Y.Takahashi, N.Kanoh, Y.Nonomura, H.Osada. Structure-Affinity Relationship Study of Bleomycins and Shble Protein Using A Chemical Array To Be Published.