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Atomistry » Chlorine » PDB 2zgd-3a2n » 2zjn | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2zgd-3a2n » 2zjn » |
Chlorine in PDB 2zjn: Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Chloro-2-Isopropoxy-3-Methoxy-Benzyl)- Piperidin-4-Yl]-2-(2-Methyl-4-Sulfamoyl-Phenoxy)-AcetamideEnzymatic activity of Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Chloro-2-Isopropoxy-3-Methoxy-Benzyl)- Piperidin-4-Yl]-2-(2-Methyl-4-Sulfamoyl-Phenoxy)-Acetamide
All present enzymatic activity of Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Chloro-2-Isopropoxy-3-Methoxy-Benzyl)- Piperidin-4-Yl]-2-(2-Methyl-4-Sulfamoyl-Phenoxy)-Acetamide:
3.4.23.46; Protein crystallography data
The structure of Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Chloro-2-Isopropoxy-3-Methoxy-Benzyl)- Piperidin-4-Yl]-2-(2-Methyl-4-Sulfamoyl-Phenoxy)-Acetamide, PDB code: 2zjn
was solved by
M.Randal,
M.B.Lam,
B.T.Fahr,
M.J.Romanowski,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Chloro-2-Isopropoxy-3-Methoxy-Benzyl)- Piperidin-4-Yl]-2-(2-Methyl-4-Sulfamoyl-Phenoxy)-Acetamide
(pdb code 2zjn). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Chloro-2-Isopropoxy-3-Methoxy-Benzyl)- Piperidin-4-Yl]-2-(2-Methyl-4-Sulfamoyl-Phenoxy)-Acetamide, PDB code: 2zjn: Chlorine binding site 1 out of 1 in 2zjnGo back to Chlorine Binding Sites List in 2zjn
Chlorine binding site 1 out
of 1 in the Crystal Structure of the Human BACE1 Catalytic Domain in Complex with N-[1-(5-Chloro-2-Isopropoxy-3-Methoxy-Benzyl)- Piperidin-4-Yl]-2-(2-Methyl-4-Sulfamoyl-Phenoxy)-Acetamide
Mono view Stereo pair view
Reference:
W.Yang,
R.V.Fucini,
B.T.Fahr,
M.Randal,
K.E.Lind,
M.B.Lam,
W.Lu,
Y.Lu,
D.R.Cary,
M.J.Romanowski.
Fragment-Based Discovery of Novel BACE1 Inhibitors Using Tethering Technology To Be Published.
Page generated: Sat Dec 12 09:30:31 2020
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