Atomistry » Chlorine » PDB 3b0n-3bfh » 3baw
Atomistry »
  Chlorine »
    PDB 3b0n-3bfh »
      3baw »

Chlorine in PDB 3baw: Human Pancreatic Alpha-Amylase Complexed with Azide

Enzymatic activity of Human Pancreatic Alpha-Amylase Complexed with Azide

All present enzymatic activity of Human Pancreatic Alpha-Amylase Complexed with Azide:
3.2.1.1;

Protein crystallography data

The structure of Human Pancreatic Alpha-Amylase Complexed with Azide, PDB code: 3baw was solved by R.Maurus, G.D.Brayer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 2.00
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 51.810, 67.360, 129.730, 90.00, 90.00, 90.00
R / Rfree (%) 16.3 / 21.4

Other elements in 3baw:

The structure of Human Pancreatic Alpha-Amylase Complexed with Azide also contains other interesting chemical elements:

Calcium (Ca) 1 atom
Sodium (Na) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human Pancreatic Alpha-Amylase Complexed with Azide (pdb code 3baw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Pancreatic Alpha-Amylase Complexed with Azide, PDB code: 3baw:

Chlorine binding site 1 out of 1 in 3baw

Go back to Chlorine Binding Sites List in 3baw
Chlorine binding site 1 out of 1 in the Human Pancreatic Alpha-Amylase Complexed with Azide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Pancreatic Alpha-Amylase Complexed with Azide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl499

b:9.4
occ:1.00
NE A:ARG195 3.1 5.2 1.0
NH2 A:ARG337 3.2 6.6 1.0
NH1 A:ARG337 3.3 6.0 1.0
O A:HOH606 3.3 6.1 1.0
NH2 A:ARG195 3.3 3.9 1.0
ND2 A:ASN298 3.4 7.2 1.0
CZ A:ARG195 3.6 4.4 1.0
CZ A:ARG337 3.7 6.2 1.0
CG2 A:THR254 3.9 7.0 1.0
CZ A:PHE256 4.0 5.6 1.0
CD A:ARG195 4.2 5.2 1.0
CB A:ASN298 4.3 6.8 1.0
CG A:ASN298 4.3 7.3 1.0
CG A:GLU233 4.3 7.2 1.0
CE2 A:PHE256 4.5 6.1 1.0
CB A:GLU233 4.7 7.0 1.0
CB A:THR254 4.7 7.7 1.0
CZ A:PHE295 4.8 6.3 1.0
O A:HOH619 4.8 9.2 1.0
OE2 A:GLU233 4.8 9.5 1.0
CD A:GLU233 4.9 9.3 1.0
CE1 A:HIS299 4.9 12.3 1.0
CE1 A:PHE256 4.9 4.9 1.0
CG A:ARG195 5.0 7.2 1.0
NH1 A:ARG195 5.0 4.9 1.0

Reference:

R.Maurus, A.Begum, L.K.Williams, J.R.Fredriksen, R.Zhang, S.G.Withers, G.D.Brayer. Alternative Catalytic Anions Differentially Modulate Human Alpha-Amylase Activity and Specificity Biochemistry V. 47 3332 2008.
ISSN: ISSN 0006-2960
PubMed: 18284212
DOI: 10.1021/BI701652T
Page generated: Sat Dec 12 09:33:00 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy