Chlorine in PDB 3bkd: High Resolution Crystal Structure of Transmembrane Domain of M2 Protein

The structure of High Resolution Crystal Structure of Transmembrane Domain of M2 Protein, PDB code: 3bkd was solved by A.L.Stouffer, R.Acharya, D.Salom, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.05
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	38.753, 56.557, 56.009, 90.00, 103.53, 90.00
R / Rfree (%)	21.9 / 26.9

The binding sites of Chlorine atom in the High Resolution Crystal Structure of Transmembrane Domain of M2 Protein (pdb code 3bkd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the High Resolution Crystal Structure of Transmembrane Domain of M2 Protein, PDB code: 3bkd:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the High Resolution Crystal Structure of Transmembrane Domain of M2 Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of High Resolution Crystal Structure of Transmembrane Domain of M2 Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl101 b:25.3 occ:1.00 OG D:SER23 2.8 24.6 1.0 OG B:SER23 3.1 26.4 1.0 OG A:SER23 3.1 27.5 1.0 OG C:SER23 3.2 22.8 1.0 CB D:SER23 3.7 27.5 1.0 CB A:SER23 3.7 29.4 1.0 CB C:SER23 3.8 24.5 1.0 CB B:SER23 3.8 27.1 1.0 CA D:SER23 4.1 27.1 1.0 CA C:SER23 4.1 25.0 1.0 CA B:SER23 4.1 27.8 1.0 CG1 C:VAL27 4.2 20.4 1.0 CG1 D:VAL27 4.3 23.2 1.0 CA A:SER23 4.3 29.8 1.0 CG1 B:VAL27 4.3 23.2 1.0 CG1 A:VAL27 4.5 20.4 1.0 O C:SER22 4.8 25.2 1.0 N D:SER23 4.8 28.5 1.0 CB D:VAL27 4.9 23.4 1.0 N B:SER23 4.9 28.4 1.0 CB C:VAL27 5.0 21.2 1.0

Chlorine binding site 2 out of 2 in the High Resolution Crystal Structure of Transmembrane Domain of M2 Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of High Resolution Crystal Structure of Transmembrane Domain of M2 Protein within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl501 b:31.4 occ:1.00 OG F:SER23 3.0 31.8 1.0 OG G:SER23 3.0 27.4 1.0 OG E:SER23 3.1 28.2 1.0 OG H:SER23 3.2 29.0 1.0 CB F:SER23 3.8 31.8 1.0 CB G:SER23 3.8 28.6 1.0 CB H:SER23 3.8 28.9 1.0 CB E:SER23 3.9 31.4 1.0 O E:HOH804 3.9 68.2 1.0 CA F:SER23 4.1 32.0 1.0 CA G:SER23 4.1 28.6 1.0 CG1 G:VAL27 4.1 20.3 1.0 CA H:SER23 4.2 29.2 1.0 CG1 H:VAL27 4.2 24.4 1.0 CG1 F:VAL27 4.3 26.0 1.0 CA E:SER23 4.3 31.3 1.0 CG1 E:VAL27 4.5 24.2 1.0 O E:SER22 4.5 35.5 1.0 N F:SER23 4.9 32.9 1.0 CB G:VAL27 4.9 21.3 1.0 CB H:VAL27 4.9 23.6 1.0 N G:SER23 4.9 29.4 1.0

A.L.Stouffer, R.Acharya, D.Salom, A.S.Levine, L.Di Costanzo, C.S.Soto, V.Tereshko, V.Nanda, S.Stayrook, W.F.Degrado. Structural Basis For the Function and Inhibition of An Influenza Virus Proton Channel Nature V. 451 596 2008.
ISSN: ISSN 0028-0836
PubMed: 18235504
DOI: 10.1038/NATURE06528