Chlorine in PDB 3c7n: Structure of the HSP110:HSC70 Nucleotide Exchange Complex

The structure of Structure of the HSP110:HSC70 Nucleotide Exchange Complex, PDB code: 3c7n was solved by J.P.Schuermann, J.Jiang, P.J.Hart, R.Sousa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.38 / 3.12
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	123.533, 169.501, 87.724, 90.00, 90.00, 90.00
R / Rfree (%)	22.4 / 28.3

The structure of Structure of the HSP110:HSC70 Nucleotide Exchange Complex also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Chlorine atom in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex (pdb code 3c7n). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex, PDB code: 3c7n:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the HSP110:HSC70 Nucleotide Exchange Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl555 b:69.1 occ:1.00 CB B:ALA191 3.0 73.8 1.0 NH1 B:ARG193 3.4 48.1 1.0 O B:GLU192 3.8 76.6 1.0 CE1 B:HIS332 4.0 55.5 1.0 NE2 B:HIS332 4.1 56.1 1.0 ND1 B:HIS332 4.2 55.9 1.0 CG B:ARG193 4.3 51.2 1.0 CA B:ALA191 4.3 73.9 1.0 CD2 B:HIS332 4.3 55.2 1.0 CG B:HIS332 4.4 54.8 1.0 O B:GLY190 4.4 86.9 1.0 CZ B:ARG193 4.5 48.7 1.0 C B:GLU192 4.5 76.5 1.0 C B:ALA191 4.6 74.1 1.0 N B:GLU192 4.6 77.2 1.0 O B:VAL189 4.9 49.1 1.0

Chlorine binding site 2 out of 3 in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the HSP110:HSC70 Nucleotide Exchange Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl556 b:65.8 occ:1.00 NE B:ARG236 3.0 22.4 1.0 NH2 B:ARG236 3.4 22.9 1.0 CZ B:ARG236 3.6 22.8 1.0 CD B:ARG236 4.1 23.2 1.0 CB B:ASN235 4.2 38.0 1.0 CG B:ARG236 4.5 24.5 1.0 O B:ASP232 4.6 32.6 1.0 ND2 B:ASN239 4.7 34.4 1.0 N B:ARG236 4.7 26.2 1.0 OD1 B:ASP232 4.8 31.5 1.0 NH1 B:ARG236 4.9 23.0 1.0

Chlorine binding site 3 out of 3 in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of the HSP110:HSC70 Nucleotide Exchange Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl557 b:48.4 occ:1.00 NE B:ARG342 3.6 31.9 1.0 NH2 B:ARG342 3.8 32.2 1.0 CG2 A:VAL28 3.9 31.6 1.0 CZ B:ARG342 4.1 31.2 1.0 OD1 B:ASN364 4.3 25.3 1.0 CD B:PRO365 4.4 34.8 1.0 CD B:ARG342 4.5 33.0 1.0 CA B:ASN364 4.5 26.9 1.0 O B:SER362 4.9 34.7 1.0 CB B:ASN364 4.9 26.8 1.0 N B:ASN364 5.0 27.0 1.0 CG B:ASN364 5.0 26.1 1.0

J.P.Schuermann, J.Jiang, J.Cuellar, O.Llorca, L.Wang, L.E.Gimenez, S.Jin, A.B.Taylor, B.Demeler, K.A.Morano, P.J.Hart, J.M.Valpuesta, E.M.Lafer, R.Sousa. Structure of the HSP110:HSC70 Nucleotide Exchange Machine Mol.Cell V. 31 232 2008.
ISSN: ISSN 1097-2765
PubMed: 18550409
DOI: 10.1016/J.MOLCEL.2008.05.006