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Chlorine in PDB 3c7p: Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237
Enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237, PDB code: 3c7p
was solved by
A.Di Fiore,
G.De Simone,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 20.00 / 1.70 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.050, 41.440, 71.670, 90.00, 104.35, 90.00 |
| R / Rfree (%) | 18.1 / 20.2 |
Other elements in 3c7p:
The structure of Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237 also contains other interesting chemical elements:
| Mercury | (Hg) | 1 atom |
| Zinc | (Zn) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237
(pdb code 3c7p). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237, PDB code: 3c7p:
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237, PDB code: 3c7p:
Chlorine binding site 1 out of 1 in 3c7p
Go back to
Chlorine Binding Sites List in 3c7p
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Human Carbonic Anhydrase II in Complex with STX237 within 5.0Å range:
|
Reference:
L.W.L.Woo,
D.S.Fischer,
C.M.Sharland,
M.Trusselle,
P.A.Foster,
S.K.Chander,
A.Di Fiore,
C.T.Supuran,
G.De Simone,
A.Purohit,
M.J.Reed,
B.V.L.Potter.
Anticancer Steroid Sulfatase Inhibitors: Synthesis of A Potent Fluorinated Second-Generation Agent, in Vitro and in Vivo Activities, Molecular Modeling, and Protein Crystallography Mol.Cancer Ther. V. 7 2435 2008.
ISSN: ISSN 1535-7163
PubMed: 18723489
DOI: 10.1158/1535-7163.MCT-08-0195
Page generated: Sat Dec 12 09:34:28 2020
ISSN: ISSN 1535-7163
PubMed: 18723489
DOI: 10.1158/1535-7163.MCT-08-0195
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