Chlorine in PDB 3c7x: Hemopexin-Like Domain of Matrix Metalloproteinase 14

All present enzymatic activity of Hemopexin-Like Domain of Matrix Metalloproteinase 14:
3.4.24.80;

The structure of Hemopexin-Like Domain of Matrix Metalloproteinase 14, PDB code: 3c7x was solved by A.Tochowicz, Y.Itoh, K.Maskos, W.Bode, P.Goettig, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.29 / 1.70
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	77.210, 77.210, 66.819, 90.00, 90.00, 120.00
R / Rfree (%)	18.5 / 20.7

The structure of Hemopexin-Like Domain of Matrix Metalloproteinase 14 also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Hemopexin-Like Domain of Matrix Metalloproteinase 14 (pdb code 3c7x). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hemopexin-Like Domain of Matrix Metalloproteinase 14, PDB code: 3c7x:

Chlorine binding site 1 out of 1 in the Hemopexin-Like Domain of Matrix Metalloproteinase 14


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hemopexin-Like Domain of Matrix Metalloproteinase 14 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1002 b:21.8 occ:1.00 OG1 A:THR325 2.7 9.0 1.0 O A:HOH19 2.9 13.6 1.0 O A:VAL326 3.0 10.1 1.0 N A:ALA371 3.1 7.8 1.0 CG2 A:THR370 3.1 17.8 1.0 O A:ALA371 3.2 9.0 1.0 CB A:ALA327 3.6 11.8 1.0 CA A:THR370 3.7 9.7 1.0 C A:VAL326 3.8 8.9 1.0 CA A:GLY465 3.9 10.6 1.0 C A:THR370 3.9 9.0 1.0 CB A:THR325 3.9 10.0 1.0 CG2 A:THR325 3.9 10.4 1.0 C A:ALA371 4.0 9.4 1.0 CA A:ALA371 4.0 6.1 1.0 CB A:THR370 4.0 20.1 1.0 CA A:ALA327 4.0 7.4 1.0 O A:ARG464 4.1 17.0 1.0 O A:HOH12 4.2 9.3 1.0 N A:ALA327 4.2 7.1 1.0 N A:VAL326 4.3 8.1 1.0 CB A:ALA371 4.5 8.0 1.0 N A:SER466 4.5 8.0 1.0 C A:GLY465 4.7 8.8 1.0 CA A:VAL326 4.8 7.2 1.0 O A:ASN369 4.8 10.9 1.0 N A:GLY465 4.9 9.0 1.0 C A:ARG464 4.9 13.1 1.0 C A:THR325 4.9 8.9 1.0 OG1 A:THR370 4.9 20.6 1.0 N A:THR370 4.9 9.4 1.0 CA A:THR325 5.0 8.8 1.0

A.Tochowicz, P.Goettig, R.Evans, R.Visse, Y.Shitomi, R.Palmisano, N.Ito, K.Richter, K.Maskos, D.Franke, D.Svergun, H.Nagase, W.Bode, Y.Itoh. The Dimer Interface of the Membrane Type 1 Matrix Metalloproteinase Hemopexin Domain: Crystal Structure and Biological Functions J.Biol.Chem. V. 286 7587 2011.
ISSN: ISSN 0021-9258
PubMed: 21193411
DOI: 10.1074/JBC.M110.178434