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Chlorine in PDB 3caj: Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide
Enzymatic activity of Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide
All present enzymatic activity of Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide, PDB code: 3caj
was solved by
A.Di Fiore,
G.De Simone,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 20.00 / 1.80 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.210, 41.360, 72.030, 90.00, 104.35, 90.00 |
| R / Rfree (%) | 18 / 21.4 |
Other elements in 3caj:
The structure of Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide also contains other interesting chemical elements:
| Mercury | (Hg) | 1 atom |
| Zinc | (Zn) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide
(pdb code 3caj). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide, PDB code: 3caj:
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide, PDB code: 3caj:
Chlorine binding site 1 out of 1 in 3caj
Go back to
Chlorine Binding Sites List in 3caj
Chlorine binding site 1 out
of 1 in the Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of the Human Carbonic Anhydrase II in Complex with Ethoxzolamide within 5.0Å range:
|
Reference:
A.Di Fiore,
C.Pedone,
J.Antel,
H.Waldeck,
A.Witte,
M.Wurl,
A.Scozzafava,
C.T.Supuran,
G.De Simone.
Carbonic Anhydrase Inhibitors: the X-Ray Crystal Structure of Ethoxzolamide Complexed to Human Isoform II Reveals the Importance of THR200 and GLN92 For Obtaining Tight-Binding Inhibitors Bioorg.Med.Chem.Lett. V. 18 2669 2008.
ISSN: ISSN 0960-894X
PubMed: 18359629
DOI: 10.1016/J.BMCL.2008.03.023
Page generated: Sat Dec 12 09:34:41 2020
ISSN: ISSN 0960-894X
PubMed: 18359629
DOI: 10.1016/J.BMCL.2008.03.023
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