Chlorine in PDB 3cla: Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution

All present enzymatic activity of Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution:
2.3.1.28;

The structure of Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution, PDB code: 3cla was solved by A.G.W.Leslie, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	6.00 / 1.75
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	107.600, 107.600, 123.600, 90.00, 90.00, 120.00
R / Rfree (%)	15.7 / n/a

The structure of Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution also contains other interesting chemical elements:

Cobalt

(Co)

2 atoms

The binding sites of Chlorine atom in the Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution (pdb code 3cla). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution, PDB code: 3cla:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl221 b:26.1 occ:0.66 CL1 A:CLM221 0.0 26.1 0.7 C1 A:CLM221 1.7 21.8 0.7 C2 A:CLM221 2.6 17.7 0.7 CL2 A:CLM221 2.8 24.7 0.7 O2 A:CLM221 2.9 13.4 0.7 O A:HOH402 3.2 63.0 1.0 ND2 A:ASN146 3.7 20.2 1.0 N2 A:CLM221 3.7 16.5 0.7 OE1 A:GLN92 3.9 23.9 1.0 C10 A:CLM221 4.2 19.5 0.7 CG A:ASN146 4.2 23.0 1.0 C11 A:CLM221 4.2 16.2 0.7 OD1 A:ASN146 4.2 21.1 1.0 CE2 A:PHE135 4.7 13.8 1.0 CZ A:PHE135 4.7 15.7 1.0 C6 A:CLM221 4.7 18.0 0.7 C9 A:CLM221 4.8 20.7 0.7 O A:HOH360 5.0 49.0 1.0 C3 A:CLM221 5.0 17.7 0.7

Chlorine binding site 2 out of 2 in the Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Refined Crystal Structure of Type III Chloramphenicol Acetyltransferase at 1.75 Angstroms Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl221 b:24.7 occ:0.66 CL2 A:CLM221 0.0 24.7 0.7 C1 A:CLM221 1.8 21.8 0.7 C2 A:CLM221 2.6 17.7 0.7 CL1 A:CLM221 2.8 26.1 0.7 O2 A:CLM221 3.1 13.4 0.7 N2 A:CLM221 3.5 16.5 0.7 CE2 A:PHE135 3.6 13.8 1.0 CB A:ALA105 3.6 8.3 1.0 CZ A:PHE135 3.8 15.7 1.0 OE1 A:GLN92 4.3 23.9 1.0 O A:HOH245 4.6 30.7 1.0 CD1 A:LEU134 4.6 12.4 1.0 CE1 A:PHE103 4.6 12.6 1.0 ND2 A:ASN146 4.7 20.2 1.0 CD2 A:PHE135 4.7 15.1 1.0 C3 A:CLM221 4.7 17.7 0.7 CD A:GLN92 4.9 17.0 1.0 CA A:ALA105 4.9 10.1 1.0

A.G.Leslie, A.G.W.Leslie. N/A N/A.
ISSN: ISSN 0022-2836
PubMed: 2187098
DOI: 10.1016/S0022-2836(05)80129-9