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Atomistry » Chlorine » PDB 3d4i-3dgo » 3db8 » |
Chlorine in PDB 3db8: Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 041Enzymatic activity of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 041
All present enzymatic activity of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 041:
2.7.11.21; Protein crystallography data
The structure of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 041, PDB code: 3db8
was solved by
R.A.Elling,
E.J.Hanan,
W.Lew,
M.J.Romanowski,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 041
(pdb code 3db8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 041, PDB code: 3db8: Chlorine binding site 1 out of 1 in 3db8Go back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 041
![]() Mono view ![]() Stereo pair view
Reference:
E.J.Hanan,
R.V.Fucini,
M.J.Romanowski,
R.A.Elling,
W.Lew,
H.E.Purkey,
E.C.Vanderporten,
W.Yang.
Design and Synthesis of 2-Amino-Isoxazolopyridines As Polo-Like Kinase Inhibitors. Bioorg.Med.Chem.Lett. V. 18 5186 2008.
Page generated: Fri Jul 11 04:24:14 2025
ISSN: ISSN 0960-894X PubMed: 18790636 DOI: 10.1016/J.BMCL.2008.08.091 |
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