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Atomistry » Chlorine » PDB 3d44-3dgc » 3dbd » |
Chlorine in PDB 3dbd: Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 094Enzymatic activity of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 094
All present enzymatic activity of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 094:
2.7.11.21; Protein crystallography data
The structure of Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 094, PDB code: 3dbd
was solved by
R.A.Elling,
K.J.Barr,
M.J.Romanowski,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 094
(pdb code 3dbd). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 094, PDB code: 3dbd: Chlorine binding site 1 out of 1 in 3dbdGo back to Chlorine Binding Sites List in 3dbd
Chlorine binding site 1 out
of 1 in the Crystal Structure of An Activated (Thr->Asp) Polo-Like Kinase 1 (PLK1) Catalytic Domain in Complex with Compound 094
Mono view Stereo pair view
Reference:
R.V.Fucini,
E.J.Hanan,
M.J.Romanowski,
R.A.Elling,
W.Lew,
K.J.Barr,
J.Zhu,
J.C.Yoburn,
Y.Liu,
B.T.Fahr,
J.Fan,
Y.Lu,
P.Pham,
I.C.Choong,
E.C.Vanderporten,
M.Bui,
H.E.Purkey,
M.J.Evanchik,
W.Yang.
Design and Synthesis of 2-Amino-Pyrazolopyridines As Polo-Like Kinase 1 Inhibitors. Bioorg.Med.Chem.Lett. V. 18 5648 2008.
Page generated: Sat Dec 12 09:38:03 2020
ISSN: ISSN 0960-894X PubMed: 18793847 DOI: 10.1016/J.BMCL.2008.08.095 |
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