Chlorine in PDB 3dfj: Crystal Structure of Human Prostasin

The structure of Crystal Structure of Human Prostasin, PDB code: 3dfj was solved by H.P.Su, K.W.Rickert, P.L.Darke, S.K.Munshi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.57 / 1.45
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	52.988, 56.241, 82.960, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 21.3

The binding sites of Chlorine atom in the Crystal Structure of Human Prostasin (pdb code 3dfj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Prostasin, PDB code: 3dfj:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human Prostasin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Prostasin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:20.4 occ:1.00 O A:HOH399 3.0 18.1 1.0 O A:HOH464 3.1 21.7 1.0 O A:HOH536 3.1 40.6 1.0 ND2 A:ASN202 3.2 13.0 1.0 CA A:GLU199 3.8 11.5 1.0 CB A:ASN202 3.8 12.1 1.0 CG A:GLU199 3.9 12.3 1.0 CG A:ASN202 4.0 12.6 1.0 CB A:GLU199 4.2 11.7 1.0 NH2 A:ARG198 4.2 16.0 1.0 NH1 A:ARG198 4.3 16.8 1.0 O A:ARG198 4.4 11.7 1.0 CZ A:ARG198 4.4 15.7 1.0 O A:GLU199 4.4 11.3 1.0 N A:GLU199 4.5 11.5 1.0 O A:HOH317 4.5 11.7 1.0 C A:GLU199 4.6 11.5 1.0 O A:HOH627 4.7 36.4 1.0 C A:ARG198 4.7 11.6 1.0 CE2 A:PHE216 4.9 16.0 1.0 CD A:GLU199 5.0 13.9 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human Prostasin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Prostasin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2 b:19.6 occ:1.00 OG A:SER76 2.9 15.1 1.0 O A:HOH502 3.0 15.3 1.0 O A:HOH571 3.1 23.5 1.0 CB A:SER76 3.5 14.1 1.0 CD1 A:TRP79 3.7 14.2 1.0 CG A:GLN78 3.7 14.8 1.0 CG A:GLU77 3.9 16.1 1.0 CG1 A:VAL285 4.0 17.3 1.0 NE1 A:TRP79 4.1 14.2 1.0 N A:GLN78 4.2 14.2 1.0 N A:GLU77 4.2 14.5 1.0 NE2 A:GLN78 4.3 15.9 1.0 O A:HOH590 4.3 23.2 1.0 CD A:GLN78 4.5 14.8 1.0 CB A:GLN78 4.6 14.4 1.0 OE2 A:GLU77 4.7 18.4 1.0 CA A:SER76 4.7 14.0 1.0 C A:SER76 4.8 14.2 1.0 CD A:GLU77 4.8 16.6 1.0 CG A:TRP79 4.8 13.6 1.0 CA A:GLN78 4.9 14.1 1.0 CA A:GLU77 4.9 15.0 1.0 CB A:GLU77 4.9 15.0 1.0 CG A:GLN289 5.0 20.3 0.5 C A:GLU77 5.0 14.5 1.0

K.W.Rickert, P.Kelley, N.J.Byrne, R.E.Diehl, D.L.Hall, A.M.Montalvo, J.C.Reid, J.M.Shipman, B.W.Thomas, S.K.Munshi, P.L.Darke, H.P.Su. Structure of Human Prostasin, A Target For the Regulation of Hypertension. J.Biol.Chem. V. 283 34864 2008.
ISSN: ISSN 0021-9258
PubMed: 18922802
DOI: 10.1074/JBC.M805262200