Chlorine in PDB 3e00: Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with GW9662, 9-Cis Retinoic Acid and NCOA2 Peptide

The structure of Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with GW9662, 9-Cis Retinoic Acid and NCOA2 Peptide, PDB code: 3e00 was solved by V.Chandra, P.Huang, Y.Hamuro, S.Raghuram, Y.Wang, T.P.Burris, F.Rastinejad, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.76 / 3.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	63.585, 146.775, 67.230, 90.00, 115.52, 90.00
R / Rfree (%)	21.4 / 27.6

The structure of Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with GW9662, 9-Cis Retinoic Acid and NCOA2 Peptide also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with GW9662, 9-Cis Retinoic Acid and NCOA2 Peptide (pdb code 3e00). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with GW9662, 9-Cis Retinoic Acid and NCOA2 Peptide, PDB code: 3e00:

Chlorine binding site 1 out of 1 in the Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with GW9662, 9-Cis Retinoic Acid and NCOA2 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Intact Ppar Gamma - Rxr Alpha Nuclear Receptor Complex on Dna Bound with GW9662, 9-Cis Retinoic Acid and NCOA2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl7123 b:0.8 occ:1.00 CL D:GW97123 0.0 0.8 1.0 C9 D:GW97123 1.8 0.8 1.0 C10 D:GW97123 2.8 0.8 1.0 C8 D:GW97123 2.8 0.8 1.0 O1 D:GW97123 3.3 0.8 1.0 SG D:CYS285 3.4 0.7 1.0 C1 D:GW97123 3.5 0.8 1.0 CE1 D:PHE282 3.7 0.2 1.0 CD1 D:PHE282 3.9 0.2 1.0 C11 D:GW97123 4.1 0.8 1.0 C13 D:GW97123 4.1 0.8 1.0 CB D:CYS285 4.2 0.7 1.0 CE D:MET364 4.3 71.8 1.0 SD D:MET364 4.4 71.8 1.0 C12 D:GW97123 4.7 0.8 1.0 CG D:MET364 4.7 71.8 1.0 CZ D:PHE282 4.7 0.2 1.0 O D:ILE281 4.8 85.6 1.0 N1 D:GW97123 4.8 0.8 1.0

V.Chandra, P.Huang, Y.Hamuro, S.Raghuram, Y.Wang, T.P.Burris, F.Rastinejad. Structure of the Intact Ppar-Gamma-Rxr- Nuclear Receptor Complex on Dna. Nature V. 456 350 2008.
ISSN: ISSN 0028-0836
PubMed: 19043829
DOI: 10.1038/NATURE07413