Chlorine in PDB 3erd: Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Diethylstilbestrol and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide

The structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Diethylstilbestrol and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide, PDB code: 3erd was solved by A.K.Shiau, D.Barstad, P.M.Loria, L.Cheng, P.J.Kushner, D.A.Agard, G.L.Greene, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.00 / 2.03
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	54.094, 82.217, 58.041, 90.00, 111.33, 90.00
R / Rfree (%)	19.6 / 24.8

The binding sites of Chlorine atom in the Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Diethylstilbestrol and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide (pdb code 3erd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Diethylstilbestrol and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide, PDB code: 3erd:

Chlorine binding site 1 out of 1 in the Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Diethylstilbestrol and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with Diethylstilbestrol and A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl601 b:23.2 occ:1.00 O A:HOH2 3.1 21.7 1.0 NH1 A:ARG352 3.2 16.7 1.0 CD A:ARG352 3.6 21.0 1.0 CD2 A:LEU327 4.0 17.7 1.0 CD1 A:LEU327 4.2 20.8 1.0 CZ A:ARG352 4.2 19.3 1.0 NE A:ARG352 4.3 20.0 1.0 CG A:ARG352 4.4 20.4 1.0 CG A:LEU327 4.5 20.1 1.0 CB A:ARG352 4.5 20.8 1.0 CB A:LEU327 4.7 24.3 1.0 O A:HOH10 4.7 19.5 1.0

A.K.Shiau, D.Barstad, P.M.Loria, L.Cheng, P.J.Kushner, D.A.Agard, G.L.Greene. The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction By Tamoxifen. Cell(Cambridge,Mass.) V. 95 927 1998.
ISSN: ISSN 0092-8674
PubMed: 9875847
DOI: 10.1016/S0092-8674(00)81717-1