Chlorine in PDB 3f0w: Human Numb-Like Protein, Phosphotyrosine Interaction Domain

The structure of Human Numb-Like Protein, Phosphotyrosine Interaction Domain, PDB code: 3f0w was solved by L.Lehtio, M.Moche, J.Andersson, C.H.Arrowsmith, H.Berglund, C.Bountra, R.Dbusam, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, A.Johansson, I.Johansson, T.Karlberg, T.Kotenyova, M.E.Nilsson, T.Nyman, C.Persson, J.Sagemark, H.Schueler, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Welin, M.Wikstrom, M.Wisniewska, P.Nordlund, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.46 / 2.70
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	55.150, 55.150, 99.350, 90.00, 90.00, 120.00
R / Rfree (%)	23.8 / 28.1

The binding sites of Chlorine atom in the Human Numb-Like Protein, Phosphotyrosine Interaction Domain (pdb code 3f0w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Numb-Like Protein, Phosphotyrosine Interaction Domain, PDB code: 3f0w:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Numb-Like Protein, Phosphotyrosine Interaction Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Numb-Like Protein, Phosphotyrosine Interaction Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:88.7 occ:1.00 NH1 A:ARG74 2.8 10.9 1.0 NH2 A:ARG198 3.6 26.1 1.0 NH2 A:ARG201 3.7 30.0 1.0 NE A:ARG198 3.8 25.0 1.0 CZ A:ARG74 4.1 10.8 1.0 CZ A:ARG198 4.2 26.0 1.0 CZ A:ARG201 4.7 29.9 1.0 NH2 A:ARG74 4.8 10.6 1.0 NE A:ARG74 4.9 10.4 1.0 CD A:ARG74 4.9 9.5 1.0

Chlorine binding site 2 out of 2 in the Human Numb-Like Protein, Phosphotyrosine Interaction Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Numb-Like Protein, Phosphotyrosine Interaction Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2 b:85.9 occ:0.50 NH1 A:ARG94 2.7 19.1 1.0 CB A:GLU52 3.3 8.3 1.0 N A:GLU52 3.4 7.8 1.0 CZ A:ARG94 3.7 20.0 1.0 CE1 A:PHE146 3.8 18.2 1.0 CA A:GLU52 3.9 8.0 1.0 NH2 A:ARG94 3.9 20.1 1.0 C A:THR51 4.2 7.5 1.0 CD1 A:PHE146 4.2 18.3 1.0 CA A:THR51 4.4 7.4 1.0 O A:GLY50 4.4 7.4 1.0 CG A:GLU52 4.6 9.2 1.0 N A:THR51 4.6 7.4 1.0 C A:GLY50 4.7 7.6 1.0 NE A:ARG94 5.0 21.1 1.0

L.Lehtio, M.Moche, J.Andersson, C.H.Arrowsmith, H.Berglund, C.Bountra, R.D Busam, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, A.Johansson, I.Johansson, T.Karlberg, T.Kotenyova, M.E.Nilsson, T.Nyman, C.Persson, J.Sagemark, H.Schueler, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Welin, M.Wikstrom, M.Wisniewska, P.Nordlund. Human Numb-Like Protein, Phosphotyrosine Interaction Domain To Be Published.