Chlorine in PDB 3fe2: Human Dead-Box Rna Helicase DDX5 (P68), Conserved Domain I in Complex with Adp

The structure of Human Dead-Box Rna Helicase DDX5 (P68), Conserved Domain I in Complex with Adp, PDB code: 3fe2 was solved by T.Karlberg, M.I.Siponen, C.H.Arrowsmith, H.Berglund, C.Bountra, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, A.Johansson, I.Johansson, T.Kotenyova, L.Lehtio, M.Moche, M.E.Nilsson, P.Nordlund, T.Nyman, C.Persson, J.Sagemark, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Welin, M.Wikstrom, M.Wisniewska, H.Schuler, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.91 / 2.60
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	84.570, 106.870, 117.320, 90.00, 90.00, 90.00
R / Rfree (%)	20.5 / 27.3

The binding sites of Chlorine atom in the Human Dead-Box Rna Helicase DDX5 (P68), Conserved Domain I in Complex with Adp (pdb code 3fe2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Dead-Box Rna Helicase DDX5 (P68), Conserved Domain I in Complex with Adp, PDB code: 3fe2:

Chlorine binding site 1 out of 1 in the Human Dead-Box Rna Helicase DDX5 (P68), Conserved Domain I in Complex with Adp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Dead-Box Rna Helicase DDX5 (P68), Conserved Domain I in Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1 b:33.4 occ:1.00 ND2 B:ASN157 3.4 17.1 1.0 SG B:CYS194 3.6 17.3 1.0 CB B:PRO102 3.9 19.1 1.0 ND2 A:ASN104 3.9 19.4 1.0 CG B:PRO102 4.0 18.9 1.0 ND2 B:ASN104 4.0 19.8 1.0 OD1 B:ASN157 4.0 15.0 1.0 CB B:CYS194 4.1 17.9 1.0 CG B:ASN157 4.2 18.3 1.0 CB B:ASN104 4.2 18.7 1.0 CG2 B:ILE153 4.4 13.9 1.0 CA B:CYS194 4.5 17.7 1.0 NH1 A:ARG195 4.5 23.5 1.0 CG B:ASN104 4.7 18.8 1.0 NH2 A:ARG195 4.7 21.7 1.0 O B:CYS194 4.9 16.6 1.0 CG A:ASN104 4.9 18.9 1.0 CG2 B:VAL105 5.0 19.0 1.0

P.Schutz, T.Karlberg, S.Van Den Berg, R.Collins, L.Lehtio, M.Hogbom, L.Holmberg-Schiavone, W.Tempel, H.W.Park, M.Hammarstrom, M.Moche, A.G.Thorsell, H.Schuler. Comparative Structural Analysis of Human Dead-Box Rna Helicases Plos One V. 5 E1279 2010.
ISSN: ESSN 1932-6203
PubMed: 20941364
DOI: 10.1371/JOURNAL.PONE.0012791