Chlorine in PDB 3fgh: Human Mitochondrial Transcription Factor A Box B

The structure of Human Mitochondrial Transcription Factor A Box B, PDB code: 3fgh was solved by T.A.Gangelhoff, P.Mungalachetty, J.Nix, M.E.A.Churchill, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.00 / 1.35
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	30.280, 99.350, 51.910, 90.00, 90.00, 90.00
R / Rfree (%)	18.8 / 21.4

The structure of Human Mitochondrial Transcription Factor A Box B also contains other interesting chemical elements:

Cadmium	(Cd)	2 atoms
Sodium	(Na)	2 atoms

The binding sites of Chlorine atom in the Human Mitochondrial Transcription Factor A Box B (pdb code 3fgh). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Mitochondrial Transcription Factor A Box B, PDB code: 3fgh:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Mitochondrial Transcription Factor A Box B


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Mitochondrial Transcription Factor A Box B within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl178 b:12.7 occ:1.00 O A:HOH46 2.4 34.2 1.0 CD A:CD1 2.5 10.6 1.0 N A:ALA119 3.2 11.5 1.0 OE2 A:GLU166 3.7 11.1 1.0 CB A:ALA119 3.7 13.8 1.0 CB A:SER118 3.9 13.7 1.0 CB A:ALA162 3.9 12.7 1.0 CA A:SER118 3.9 12.6 1.0 CL A:CL179 4.0 11.8 1.0 CA A:ALA119 4.1 11.4 1.0 C A:SER118 4.1 11.8 1.0 CD A:GLU166 4.6 10.2 1.0 OE1 A:GLU166 4.7 10.1 1.0 OG A:SER118 5.0 12.7 1.0 N A:TYR120 5.0 14.2 0.5 N A:TYR120 5.0 13.4 0.5

Chlorine binding site 2 out of 2 in the Human Mitochondrial Transcription Factor A Box B


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Mitochondrial Transcription Factor A Box B within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl179 b:11.8 occ:1.00 O A:HOH46 2.3 34.2 1.0 CD A:CD1 2.5 10.6 1.0 OE2 A:GLU166 3.5 11.1 1.0 OE1 A:GLU166 3.9 10.1 1.0 CD A:GLU166 3.9 10.2 1.0 CL A:CL178 4.0 12.7 1.0 NH2 A:ARG115 4.1 11.7 1.0 CZ A:ARG115 4.9 11.8 1.0

T.A.Gangelhoff, P.S.Mungalachetty, J.C.Nix, M.E.Churchill. Structural Analysis and Dna Binding of the Hmg Domains of the Human Mitochondrial Transcription Factor A Nucleic Acids Res. V. 37 3153 2009.
ISSN: ISSN 0305-1048
PubMed: 19304746
DOI: 10.1093/NAR/GKP157