Chlorine in PDB 3fo4: Crystal Structure of Guanine Riboswitch C74U Mutant Bound to 6-Chloroguanine

The structure of Crystal Structure of Guanine Riboswitch C74U Mutant Bound to 6-Chloroguanine, PDB code: 3fo4 was solved by S.D.Gilbert, R.T.Batey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.97 / 1.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	132.600, 35.170, 41.790, 90.00, 90.38, 90.00
R / Rfree (%)	22.6 / 24.9

The structure of Crystal Structure of Guanine Riboswitch C74U Mutant Bound to 6-Chloroguanine also contains other interesting chemical elements:

Cobalt

(Co)

12 atoms

The binding sites of Chlorine atom in the Crystal Structure of Guanine Riboswitch C74U Mutant Bound to 6-Chloroguanine (pdb code 3fo4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Guanine Riboswitch C74U Mutant Bound to 6-Chloroguanine, PDB code: 3fo4:

Chlorine binding site 1 out of 1 in the Crystal Structure of Guanine Riboswitch C74U Mutant Bound to 6-Chloroguanine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Guanine Riboswitch C74U Mutant Bound to 6-Chloroguanine within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl91 b:6.6 occ:1.00 CL6 A:6GU91 0.0 6.6 1.0 C6 A:6GU91 1.7 12.5 1.0 N1 A:6GU91 2.7 16.7 1.0 C5 A:6GU91 2.7 14.1 1.0 O A:HOH393 3.1 40.3 1.0 N7 A:6GU91 3.2 13.6 1.0 O4 A:U74 3.3 25.8 1.0 O A:HOH320 3.3 20.6 1.0 O A:HOH335 3.3 27.9 1.0 N6 A:A73 3.5 25.2 1.0 O A:HOH309 3.5 23.3 1.0 O2' A:U22 3.6 27.6 1.0 N6 A:A21 3.8 21.3 1.0 C6 A:A21 3.8 24.3 1.0 N1 A:A21 3.9 25.1 1.0 C2 A:6GU91 3.9 17.5 1.0 C4 A:6GU91 4.0 14.5 1.0 N3 A:U74 4.0 27.8 1.0 C4 A:U74 4.1 27.8 1.0 O2 A:U22 4.1 27.7 1.0 C5 A:A21 4.4 25.0 1.0 N3 A:6GU91 4.4 18.1 1.0 C2 A:A21 4.5 25.4 1.0 C6 A:A73 4.5 27.2 1.0 C8 A:6GU91 4.5 14.1 1.0 N3 A:U75 4.7 28.1 1.0 O A:HOH415 4.7 36.5 1.0 C2' A:U22 4.9 27.9 1.0 N9 A:6GU91 4.9 14.7 1.0 C4 A:A21 4.9 26.0 1.0 C2 A:U22 5.0 28.0 1.0 O A:HOH498 5.0 34.3 1.0 N2 A:6GU91 5.0 20.5 1.0 O4 A:U75 5.0 27.2 1.0

S.D.Gilbert, F.E.Reyes, A.L.Edwards, R.T.Batey. Adaptive Ligand Binding By the Purine Riboswitch in the Recognition of Guanine and Adenine Analogs. Structure V. 17 857 2009.
ISSN: ISSN 0969-2126
PubMed: 19523903
DOI: 10.1016/J.STR.2009.04.009