Chlorine in PDB 3fo5: Human Start Domain of Acyl-Coenzyme A Thioesterase 11 (ACOT11)

The structure of Human Start Domain of Acyl-Coenzyme A Thioesterase 11 (ACOT11), PDB code: 3fo5 was solved by M.I.Siponen, L.Lehtio, C.H.Arrowsmith, H.Berglund, C.Bountra, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, A.Johansson, I.Johansson, T.Karlberg, T.Kotenyova, M.Moche, M.E.Nilsson, P.Nordlund, T.Nyman, C.Persson, J.Sagemark, A.G.Thorsell, L.Tresaugues, S.Van-Den-Berg, J.Weigelt, M.Welin, M.Wikstrom, M.Wisniewska, H.Shueler, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.47 / 2.00
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	52.440, 130.080, 165.230, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / 25.1

The binding sites of Chlorine atom in the Human Start Domain of Acyl-Coenzyme A Thioesterase 11 (ACOT11) (pdb code 3fo5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Start Domain of Acyl-Coenzyme A Thioesterase 11 (ACOT11), PDB code: 3fo5:

Chlorine binding site 1 out of 1 in the Human Start Domain of Acyl-Coenzyme A Thioesterase 11 (ACOT11)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Start Domain of Acyl-Coenzyme A Thioesterase 11 (ACOT11) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:46.4 occ:1.00 O A:HOH122 3.2 30.4 1.0 N A:THR483 3.2 17.8 1.0 ND1 A:HIS482 3.2 16.5 1.0 OG1 A:THR483 3.5 19.4 1.0 CB A:HIS482 3.5 16.8 1.0 CA A:HIS482 3.6 16.6 1.0 N A:LYS484 3.6 20.1 1.0 CD A:ARG523 3.7 23.8 1.0 NE A:ARG523 3.7 24.8 1.0 CG A:HIS482 3.8 17.0 1.0 C A:HIS482 3.9 17.3 1.0 CB A:LYS484 4.0 21.6 1.0 CA A:THR483 4.1 18.7 1.0 C A:THR483 4.3 19.8 1.0 CE1 A:HIS482 4.4 20.1 1.0 CA A:LYS484 4.4 20.9 1.0 NE1 B:TRP535 4.4 23.5 1.0 CB A:THR483 4.4 19.2 1.0 CG A:LYS484 4.6 26.0 1.0 O A:LYS484 4.6 19.2 1.0 CG A:ARG523 4.7 20.3 1.0 CZ A:ARG523 4.7 26.2 1.0 O A:GLY481 4.8 16.2 1.0 CD1 B:TRP535 4.9 21.6 1.0 N A:HIS482 4.9 16.1 1.0 CD A:LYS484 4.9 30.4 1.0 CE2 B:TRP535 5.0 22.3 1.0

A.G.Thorsell, W.H.Lee, C.Persson, M.I.Siponen, M.Nilsson, R.D.Busam, T.Kotenyova, H.Schuler, L.Lehtio. Comparative Structural Analysis of Lipid Binding Start Domains. Plos One V. 6 19521 2011.
ISSN: ESSN 1932-6203
PubMed: 21738568
DOI: 10.1371/JOURNAL.PONE.0019521