Chlorine in PDB 3gg3: Crystal Structure of the Bromodomain of Human Pcaf

All present enzymatic activity of Crystal Structure of the Bromodomain of Human Pcaf:
2.3.1.48;

The structure of Crystal Structure of the Bromodomain of Human Pcaf, PDB code: 3gg3 was solved by P.Filippakopoulos, T.Keates, S.Picaud, K.Rehana, O.Fedorov, E.Ugochukwu, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, J.Weigelt, C.Bountra, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.74 / 2.25
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	99.226, 99.226, 101.137, 90.00, 90.00, 120.00
R / Rfree (%)	20.7 / 24.5

The binding sites of Chlorine atom in the Crystal Structure of the Bromodomain of Human Pcaf (pdb code 3gg3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Bromodomain of Human Pcaf, PDB code: 3gg3:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Bromodomain of Human Pcaf


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Bromodomain of Human Pcaf within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:63.5 occ:1.00 NH2 A:ARG780 4.2 32.1 1.0 OH A:TYR729 4.3 35.9 1.0 CZ A:TYR729 4.7 21.7 1.0 CE2 A:TYR729 4.9 34.5 1.0

P.Filippakopoulos, S.Picaud, M.Mangos, T.Keates, J.P.Lambert, D.Barsyte-Lovejoy, I.Felletar, R.Volkmer, S.Muller, T.Pawson, A.C.Gingras, C.H.Arrowsmith, S.Knapp. Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family. Cell(Cambridge,Mass.) V. 149 214 2012.
ISSN: ISSN 0092-8674
PubMed: 22464331
DOI: 10.1016/J.CELL.2012.02.013