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Atomistry » Chlorine » PDB 3hl7-3hwg » 3hvh | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3hl7-3hwg » 3hvh » |
Chlorine in PDB 3hvh: Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate InhibitorEnzymatic activity of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor
All present enzymatic activity of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor:
2.1.1.6; Protein crystallography data
The structure of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor, PDB code: 3hvh
was solved by
A.Ehler,
D.Schlatter,
M.Stihle,
J.Benz,
M.G.Rudolph,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3hvh:
The structure of Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor
(pdb code 3hvh). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor, PDB code: 3hvh: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 3hvhGo back to Chlorine Binding Sites List in 3hvh
Chlorine binding site 1 out
of 3 in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 3hvhGo back to Chlorine Binding Sites List in 3hvh
Chlorine binding site 2 out
of 3 in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 3hvhGo back to Chlorine Binding Sites List in 3hvh
Chlorine binding site 3 out
of 3 in the Rat Catechol O-Methyltransferase in Complex with A Catechol-Type, N6- Methyladenine-Containing Bisubstrate Inhibitor
Mono view Stereo pair view
Reference:
M.Ellermann,
R.Jakob-Roetne,
C.Lerner,
E.Borroni,
D.Schlatter,
D.Roth,
A.Ehler,
M.G.Rudolph,
F.Diederich.
Molecular Recognition at the Active Site of Catechol-O-Methyltransferase: Energetically Favorable Replacement of A Water Molecule Imported By A Bisubstrate Inhibitor. Angew.Chem.Int.Ed.Engl. V. 48 9092 2009.
Page generated: Sat Dec 12 09:46:31 2020
ISSN: ISSN 1433-7851 PubMed: 19882607 DOI: 10.1002/ANIE.200904410 |
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