Chlorine in PDB 3i08: Crystal Structure of the S1-Cleaved NOTCH1 Negative Regulatory Region (Nrr)

The structure of Crystal Structure of the S1-Cleaved NOTCH1 Negative Regulatory Region (Nrr), PDB code: 3i08 was solved by W.R.Gordon, S.C.Blacklow, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.32 / 3.20
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	65.868, 65.868, 322.586, 90.00, 90.00, 90.00
R / Rfree (%)	22.9 / 28.6

The structure of Crystal Structure of the S1-Cleaved NOTCH1 Negative Regulatory Region (Nrr) also contains other interesting chemical elements:

Calcium

(Ca)

6 atoms

The binding sites of Chlorine atom in the Crystal Structure of the S1-Cleaved NOTCH1 Negative Regulatory Region (Nrr) (pdb code 3i08). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the S1-Cleaved NOTCH1 Negative Regulatory Region (Nrr), PDB code: 3i08:

Chlorine binding site 1 out of 1 in the Crystal Structure of the S1-Cleaved NOTCH1 Negative Regulatory Region (Nrr)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the S1-Cleaved NOTCH1 Negative Regulatory Region (Nrr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1668 b:76.0 occ:1.00 CA A:ASP1486 3.1 79.9 1.0 CB A:ASP1486 3.3 80.5 1.0 NE1 A:TRP1475 3.3 81.3 1.0 N A:TRP1488 3.3 76.8 1.0 C A:ASP1486 3.3 79.2 1.0 CB A:TRP1488 3.5 76.3 1.0 CE3 A:TRP1488 3.5 77.7 1.0 N A:PRO1487 3.6 78.3 1.0 CD2 A:HIS1471 3.7 90.7 1.0 CD A:PRO1487 3.7 77.8 1.0 CA A:TRP1488 3.8 76.6 1.0 CD1 A:TRP1475 3.9 82.7 1.0 OD1 A:ASP1486 3.9 85.0 1.0 O A:ASP1486 3.9 79.3 1.0 NE2 A:HIS1471 4.1 90.1 1.0 CG A:ASP1486 4.1 82.5 1.0 C A:TRP1488 4.2 76.7 1.0 CD2 A:TRP1488 4.3 77.5 1.0 CG A:TRP1488 4.3 76.6 1.0 C A:PRO1487 4.3 77.3 1.0 N A:LYS1489 4.4 76.8 1.0 CE2 A:TRP1475 4.4 79.7 1.0 N A:ASP1486 4.5 80.0 1.0 CA A:PRO1487 4.5 77.8 1.0 CZ3 A:TRP1488 4.6 76.6 1.0 O A:TRP1488 4.8 76.7 1.0 CG A:HIS1471 4.8 90.6 1.0 CZ2 A:TRP1475 5.0 80.1 1.0

W.R.Gordon, D.Vardar-Ulu, S.L'heureux, T.Ashworth, M.J.Malecki, C.Sanchez-Irizarry, D.G.Mcarthur, G.Histen, J.L.Mitchell, J.C.Aster, S.C.Blacklow. Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human NOTCH1 and NOTCH2. Plos One V. 4 E6613 2009.
ISSN: ESSN 1932-6203
PubMed: 19701457
DOI: 10.1371/JOURNAL.PONE.0006613