Chlorine in PDB 3ii2: Structure of ORF157 From Acidianus Filamentous Virus 1

The structure of Structure of ORF157 From Acidianus Filamentous Virus 1, PDB code: 3ii2 was solved by A.Goulet, S.Porciero, D.Prangishvili, H.Van Tilbeurgh, C.Cambillau, V.Campanacci, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.35 / 2.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	65.637, 65.637, 85.568, 90.00, 90.00, 120.00
R / Rfree (%)	17 / 23.7

The structure of Structure of ORF157 From Acidianus Filamentous Virus 1 also contains other interesting chemical elements:

Nickel	(Ni)	3 atoms
Mercury	(Hg)	2 atoms

The binding sites of Chlorine atom in the Structure of ORF157 From Acidianus Filamentous Virus 1 (pdb code 3ii2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of ORF157 From Acidianus Filamentous Virus 1, PDB code: 3ii2:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Structure of ORF157 From Acidianus Filamentous Virus 1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of ORF157 From Acidianus Filamentous Virus 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl163 b:13.1 occ:0.47 O A:HOH225 3.0 37.2 1.0 HG A:HG161 3.1 20.6 0.4 NE A:ARG87 3.2 29.9 0.6 OE2 A:GLU85 3.3 30.8 0.8 NH2 A:ARG87 3.6 23.3 0.7 CD1 A:TRP75 3.7 23.8 1.0 NE1 A:TRP75 3.8 33.4 1.0 ND1 A:HIS77 3.8 26.7 1.0 CZ A:ARG87 3.9 27.4 0.5 CD A:GLU85 3.9 32.9 0.0 CB A:HIS77 4.0 24.8 1.0 CG A:HIS77 4.1 24.1 1.0 CD A:ARG87 4.2 33.7 1.0 OE1 A:GLU85 4.4 34.9 0.9 CG A:GLU85 4.6 32.5 0.2 CE1 A:HIS77 4.7 28.9 1.0 CG A:ARG87 4.8 38.9 1.0 CG A:TRP75 4.9 25.3 1.0

Chlorine binding site 2 out of 3 in the Structure of ORF157 From Acidianus Filamentous Virus 1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of ORF157 From Acidianus Filamentous Virus 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl167 b:70.3 occ:1.00 O A:HOH289 3.4 40.0 1.0 CB A:ASN65 3.7 39.1 1.0 ND2 A:ASN65 3.9 44.4 1.0 NE2 A:GLN66 4.2 34.0 1.0 O A:HOH231 4.3 38.2 1.0 CG A:ASN65 4.3 45.8 1.0

Chlorine binding site 3 out of 3 in the Structure of ORF157 From Acidianus Filamentous Virus 1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of ORF157 From Acidianus Filamentous Virus 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl168 b:67.2 occ:1.00 OG1 A:THR17 3.2 48.2 1.0 NE2 A:HIS123 3.6 64.1 1.0 N A:THR17 3.9 43.7 1.0 CB A:THR17 4.2 50.5 1.0 CB A:LEU16 4.2 39.6 1.0 CE1 A:HIS123 4.4 62.0 1.0 CA A:LEU16 4.7 37.6 1.0 CA A:THR17 4.7 42.9 1.0 CD2 A:LEU16 4.7 50.7 1.0 CD2 A:HIS123 4.7 61.2 1.0 C A:LEU16 4.8 38.3 1.0 CZ A:PHE122 4.9 60.3 1.0 CG A:LEU16 4.9 48.4 1.0

A.Goulet, M.Pina, P.Redder, D.Prangishvili, L.Vera, J.Lichiere, N.Leulliot, H.Van Tilbeurgh, M.Ortiz-Lombardia, V.Campanacci, C.Cambillau. ORF157 From the Archaeal Virus Acidianus Filamentous Virus 1 Defines A New Class of Nuclease J.Virol. V. 84 5025 2010.
ISSN: ISSN 0022-538X
PubMed: 20200253
DOI: 10.1128/JVI.01664-09