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Atomistry » Chlorine » PDB 3idv-3ilf » 3ika | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3idv-3ilf » 3ika » |
Chlorine in PDB 3ika: Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to WZ4002Enzymatic activity of Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to WZ4002
All present enzymatic activity of Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to WZ4002:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to WZ4002, PDB code: 3ika
was solved by
C.-H.Yun,
M.J.Eck,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to WZ4002
(pdb code 3ika). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to WZ4002, PDB code: 3ika: Chlorine binding site 1 out of 1 in 3ikaGo back to Chlorine Binding Sites List in 3ika
Chlorine binding site 1 out
of 1 in the Crystal Structure of Egfr 696-1022 T790M Mutant Covalently Binding to WZ4002
Mono view Stereo pair view
Reference:
W.Zhou,
D.Ercan,
L.Chen,
C.H.Yun,
D.Li,
M.Capelletti,
A.B.Cortot,
L.Chirieac,
R.E.Iacob,
R.Padera,
J.R.Engen,
K.K.Wong,
M.J.Eck,
N.S.Gray,
P.A.Janne.
Novel Mutant-Selective Egfr Kinase Inhibitors Against Egfr T790M. Nature V. 462 1070 2009.
Page generated: Sat Dec 12 09:48:15 2020
ISSN: ISSN 0028-0836 PubMed: 20033049 DOI: 10.1038/NATURE08622 |
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