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Atomistry » Chlorine » PDB 3isv-3jpw » 3iw8 » |
Chlorine in PDB 3iw8: Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-UreaEnzymatic activity of Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-Urea
All present enzymatic activity of Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-Urea:
2.7.11.24; Protein crystallography data
The structure of Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-Urea, PDB code: 3iw8
was solved by
C.Gruetter,
J.R.Simard,
D.Rauh,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3iw8:
The structure of Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-Urea also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-Urea
(pdb code 3iw8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-Urea, PDB code: 3iw8: Chlorine binding site 1 out of 1 in 3iw8Go back to Chlorine Binding Sites List in 3iw8
Chlorine binding site 1 out
of 1 in the Structure of Inactive Human P38 Map Kinase in Complex with A Thiazole-Urea
Mono view Stereo pair view
Reference:
J.R.Simard,
C.Gruetter,
V.Pawar,
B.Aust,
A.Wolf,
M.Rabiller,
S.Wulfert,
A.Robubi,
S.Kluter,
C.Ottmann,
D.Rauh.
High-Throughput Screening to Identify Inhibitors Which Stabilize Inactive Kinase Conformations in P38ALPHA J.Am.Chem.Soc. V. 131 18478 2009.
Page generated: Sat Dec 12 09:49:09 2020
ISSN: ISSN 0002-7863 PubMed: 19950957 DOI: 10.1021/JA907795Q |
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