Chlorine in PDB 3l03: Crystal Structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and Estetrol (Estra-1,3,5(10)-Triene-3,15 Alpha, 16ALPHA,17BETA-Tetrol)

The structure of Crystal Structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and Estetrol (Estra-1,3,5(10)-Triene-3,15 Alpha, 16ALPHA,17BETA-Tetrol), PDB code: 3l03 was solved by S.S.Rajan, Y.Kim, K.Vanek, A.Joachimiak, G.L.Greene, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.95 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.027, 84.203, 58.762, 90.00, 109.08, 90.00
R / Rfree (%)	17.6 / 22

The binding sites of Chlorine atom in the Crystal Structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and Estetrol (Estra-1,3,5(10)-Triene-3,15 Alpha, 16ALPHA,17BETA-Tetrol) (pdb code 3l03). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and Estetrol (Estra-1,3,5(10)-Triene-3,15 Alpha, 16ALPHA,17BETA-Tetrol), PDB code: 3l03:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and Estetrol (Estra-1,3,5(10)-Triene-3,15 Alpha, 16ALPHA,17BETA-Tetrol)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and Estetrol (Estra-1,3,5(10)-Triene-3,15 Alpha, 16ALPHA,17BETA-Tetrol) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:41.1 occ:1.00 O A:HOH18 3.0 29.5 1.0 O A:HOH54 3.0 23.6 1.0 NH1 A:ARG352 3.3 39.0 1.0 CD A:ARG352 3.7 33.2 1.0 CD2 A:LEU327 4.0 33.5 1.0 CD1 A:LEU327 4.2 28.8 1.0 CZ A:ARG352 4.3 41.7 1.0 NE A:ARG352 4.5 33.5 1.0 CG A:LEU327 4.5 34.2 1.0 CG A:ARG352 4.6 32.6 1.0 CB A:LEU327 4.6 31.9 1.0 CB A:ARG352 4.6 28.3 1.0

S.S.Rajan, Y.Kim, K.Vanek, A.Joachimiak, G.L.Greene. Crystal Structure of Human Estrogen Receptor Alpha Ligand-Binding Domain in Complex with A Glucocorticoid Receptor Interacting Protein 1 Nr Box II Peptide and Estra-1,3,5(10)-Triene-3,15 Alpha,16ALPHA,17BETA-Tetrol To Be Published.