Chlorine in PDB 3l5i: Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)

The structure of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6), PDB code: 3l5i was solved by N.J.Kershaw, J.-G.Zhang, T.P.J.Garrett, P.E.Czabotar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.75 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	41.565, 75.347, 107.185, 90.00, 90.00, 90.00
R / Rfree (%)	18.1 / 22.2

The binding sites of Chlorine atom in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) (pdb code 3l5i). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6), PDB code: 3l5i:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl591 b:53.9 occ:1.00 N A:ASN511 3.2 23.1 1.0 N A:GLU512 3.5 28.8 1.0 N A:LYS510 3.6 24.2 1.0 C A:GLY509 3.8 26.3 1.0 O A:HOH652 3.8 47.9 1.0 CA A:GLY509 3.9 28.4 1.0 CA A:ASN511 3.9 25.0 1.0 CB A:GLU512 3.9 31.5 1.0 C A:ASN511 3.9 25.9 1.0 CB A:ASN511 4.0 24.4 1.0 CG A:GLU512 4.1 43.0 1.0 C A:LYS510 4.2 24.1 1.0 CA A:LYS510 4.3 27.4 1.0 CA A:GLU512 4.3 28.6 1.0 O A:GLY509 4.6 24.3 1.0 CB A:LYS510 4.6 33.4 1.0 OD1 A:ASN511 4.6 34.7 1.0 CD A:GLU512 4.6 47.2 1.0 CG A:ASN511 4.6 35.8 1.0 O2 A:EDO15 4.7 58.2 1.0 O A:GLU512 4.8 29.6 1.0 N A:GLY509 4.8 27.9 1.0 C1 A:EDO15 4.8 60.3 1.0 OE1 A:GLU512 4.8 40.9 1.0 O A:ASN511 4.9 26.0 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl592 b:50.0 occ:1.00 N A:LYS489 3.0 18.0 1.0 CG1 A:ILE488 3.5 42.1 1.0 CB A:LYS489 3.8 15.5 1.0 O A:LYS489 3.8 17.5 1.0 CA A:LYS489 3.8 13.9 1.0 CA A:ILE488 3.9 17.3 1.0 C A:ILE488 3.9 21.7 1.0 CE A:LYS489 4.0 42.6 1.0 CD1 A:ILE488 4.2 53.1 1.0 CG A:LYS489 4.2 24.0 1.0 C A:LYS489 4.3 17.4 1.0 CB A:ILE488 4.3 21.6 1.0 O A:HOH183 4.6 29.1 1.0 CD A:LYS489 4.8 32.3 1.0 O A:HOH170 5.0 53.0 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl593 b:26.8 occ:1.00 OG A:SER309 3.0 19.1 1.0 O A:HOH606 3.0 50.6 1.0 N A:GLN450 3.2 15.0 1.0 NH2 A:ARG461 3.5 26.3 1.0 O A:HOH605 3.6 45.5 1.0 CA A:GLN449 3.7 15.1 1.0 CB A:SER309 3.8 18.3 1.0 CB A:GLN449 3.9 18.0 1.0 C A:GLN449 4.0 17.7 1.0 O A:GLN450 4.0 21.1 1.0 CB A:GLN450 4.1 18.1 1.0 CA A:GLN450 4.2 15.8 1.0 CD A:LYS330 4.2 40.3 1.0 CZ A:ARG461 4.5 28.1 1.0 C A:GLN450 4.6 21.0 1.0 NE A:ARG461 4.6 30.1 1.0 CG A:LYS330 4.8 30.4 1.0 CG A:GLN449 5.0 16.5 1.0 O A:HOH299 5.0 51.7 1.0

Y.Xu, N.J.Kershaw, C.S.Luo, P.Soo, M.J.Pocock, P.E.Czabotar, D.J.Hilton, N.A.Nicola, T.P.Garrett, J.G.Zhang. Crystal Structure of the Entire Ectodomain of GP130: Insights Into the Molecular Assembly of the Tall Cytokine Receptor Complexes. J.Biol.Chem. V. 285 21214 2010.
ISSN: ISSN 0021-9258
PubMed: 20489211
DOI: 10.1074/JBC.C110.129502