Chlorine in PDB 3l5j: Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)

The structure of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6), PDB code: 3l5j was solved by N.J.Kershaw, J.-G.Zhang, T.P.J.Garrett, P.E.Czabotar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.15 / 3.04
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	102.936, 89.221, 106.877, 90.00, 117.72, 90.00
R / Rfree (%)	21.3 / 26.5

The binding sites of Chlorine atom in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) (pdb code 3l5j). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6), PDB code: 3l5j:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl589 b:24.2 occ:1.00 OG A:SER309 3.0 12.2 1.0 NH2 A:ARG461 3.3 19.6 1.0 N A:GLN450 3.4 11.2 1.0 CB A:SER309 3.8 10.4 1.0 CB A:GLN450 3.9 9.2 1.0 O A:GLN450 3.9 13.8 1.0 CA A:GLN449 4.1 8.6 1.0 CB A:GLN449 4.1 9.5 1.0 CA A:GLN450 4.1 11.1 1.0 C A:GLN449 4.1 9.4 1.0 CZ A:ARG461 4.3 26.4 1.0 CG A:LYS330 4.4 13.5 1.0 CD A:LYS330 4.5 19.7 1.0 C A:GLN450 4.5 13.9 1.0 NE A:ARG461 4.5 25.3 1.0 CE A:LYS330 4.6 12.1 1.0 CB A:LYS330 5.0 11.7 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1 b:29.6 occ:1.00 N B:GLN450 3.1 19.2 1.0 OG B:SER309 3.2 27.1 1.0 NH2 B:ARG461 3.6 24.2 1.0 CA B:GLN449 3.7 15.9 1.0 CD B:LYS330 3.7 20.2 1.0 CB B:GLN449 3.8 18.8 1.0 C B:GLN449 3.9 22.8 1.0 CB B:SER309 3.9 24.8 1.0 O B:GLN450 4.0 27.2 1.0 CA B:GLN450 4.1 17.8 1.0 CB B:GLN450 4.2 17.1 1.0 NE B:ARG461 4.2 17.0 1.0 CZ B:ARG461 4.4 21.9 1.0 CE B:LYS330 4.4 19.9 1.0 C B:GLN450 4.5 23.0 1.0 CG B:GLN449 4.9 21.3 1.0 CG B:LYS330 4.9 19.2 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl589 b:62.9 occ:1.00 N B:GLN494 3.5 34.9 1.0 O B:TYR491 3.6 29.8 1.0 NE2 B:GLN494 3.6 29.9 1.0 CA B:LYS493 4.0 27.6 1.0 CG B:GLN494 4.0 27.5 1.0 O B:LEU492 4.0 28.0 1.0 CG B:PRO412 4.0 17.5 1.0 C B:LEU492 4.1 28.1 1.0 N B:LYS493 4.1 28.6 1.0 CB B:GLN494 4.2 24.3 1.0 C B:LYS493 4.2 31.7 1.0 CD B:GLN494 4.2 32.5 1.0 C B:TYR491 4.2 26.4 1.0 CB B:TYR491 4.2 24.7 1.0 CA B:GLN494 4.5 28.7 1.0 CA B:TYR491 4.8 22.1 1.0 N B:LEU492 4.9 24.7 1.0 CD B:PRO412 4.9 19.4 1.0 CA B:LEU492 4.9 25.8 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Fniii Domains of Human GP130 (Domains 4-6) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl590 b:50.9 occ:1.00 NE B:ARG537 3.3 36.3 1.0 NH1 B:ARG569 3.6 30.0 1.0 NH2 B:ARG537 3.7 27.9 1.0 CD B:ARG569 3.9 23.1 1.0 O B:MET567 3.9 27.0 1.0 CZ B:ARG537 3.9 33.4 1.0 OE1 B:GLU543 4.0 32.1 1.0 CG B:ARG569 4.0 22.9 1.0 O B:PHE535 4.2 28.8 1.0 CG B:ARG537 4.2 31.9 1.0 C B:MET567 4.3 32.1 1.0 CD B:ARG537 4.3 31.0 1.0 CB B:PHE535 4.4 27.8 1.0 C B:PHE535 4.4 27.8 1.0 CB B:MET567 4.5 25.9 1.0 C B:VAL568 4.5 27.7 1.0 CB B:ARG569 4.5 26.4 1.0 CZ B:ARG569 4.6 23.8 1.0 CA B:TYR536 4.6 31.7 1.0 N B:VAL568 4.6 30.1 1.0 CA B:VAL568 4.7 28.2 1.0 N B:ARG569 4.7 26.7 1.0 N B:TYR536 4.7 31.2 1.0 NE B:ARG569 4.7 20.1 1.0 O B:VAL568 4.8 25.8 1.0 OE2 B:GLU583 4.9 40.5 1.0

Y.Xu, N.J.Kershaw, C.S.Luo, P.Soo, M.J.Pocock, P.E.Czabotar, D.J.Hilton, N.A.Nicola, T.P.Garrett, J.G.Zhang. Crystal Structure of the Entire Ectodomain of GP130: Insights Into the Molecular Assembly of the Tall Cytokine Receptor Complexes. J.Biol.Chem. V. 285 21214 2010.
ISSN: ISSN 0021-9258
PubMed: 20489211
DOI: 10.1074/JBC.C110.129502