Chlorine in PDB 3l9g: Urate Oxidase Complexed with Uric Acid and Chloride

All present enzymatic activity of Urate Oxidase Complexed with Uric Acid and Chloride:
1.7.3.3;

The structure of Urate Oxidase Complexed with Uric Acid and Chloride, PDB code: 3l9g was solved by T.Prange, N.Colloc'h, L.Gabison, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.75
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	77.737, 94.941, 104.445, 90.00, 90.00, 90.00
R / Rfree (%)	17.9 / 20.8

The structure of Urate Oxidase Complexed with Uric Acid and Chloride also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Urate Oxidase Complexed with Uric Acid and Chloride (pdb code 3l9g). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Urate Oxidase Complexed with Uric Acid and Chloride, PDB code: 3l9g:

Chlorine binding site 1 out of 1 in the Urate Oxidase Complexed with Uric Acid and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Urate Oxidase Complexed with Uric Acid and Chloride within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl800 b:16.1 occ:1.00 ND2 A:ASN254 3.2 13.2 1.0 C5 A:URC300 3.3 13.2 1.0 C4 A:URC300 3.3 11.0 1.0 CA A:GLY286 3.4 12.0 1.0 CB A:ASN254 3.5 10.9 1.0 N9 A:URC300 3.6 13.1 1.0 N7 A:URC300 3.7 12.5 1.0 N3 A:URC300 3.7 9.9 1.0 C8 A:URC300 3.8 12.1 1.0 CE1 A:HIS256 3.8 13.8 1.0 C6 A:URC300 3.8 15.7 1.0 CG A:ASN254 3.8 12.6 1.0 N1 A:URC300 4.1 14.3 1.0 C2 A:URC300 4.1 13.9 1.0 CD1 A:ILE288 4.1 12.6 1.0 N A:GLY286 4.1 13.2 1.0 NE2 A:HIS256 4.4 14.3 1.0 C A:GLY286 4.4 10.3 1.0 O13 A:URC300 4.4 15.0 1.0 O24 A:URC300 4.5 15.9 1.0 CG1 A:ILE288 4.6 11.1 1.0 CA A:ASN254 4.8 8.4 1.0 N A:LEU287 4.9 10.8 1.0 ND1 A:HIS256 4.9 12.3 1.0 O11 A:URC300 4.9 12.2 1.0

L.Gabison, M.Chiadmi, M.El Hajji, B.Castro, N.Colloc'h, T.Prange. Near-Atomic Resolution Structures of Urate Oxidase Complexed with Its Substrate and Analogues: the Protonation State of the Ligand. Acta Crystallogr.,Sect.D V. 66 714 2010.
ISSN: ISSN 0907-4449
PubMed: 20516624
DOI: 10.1107/S090744491001142X