Atomistry » Chlorine » PDB 3lcd-3lnr » 3lj7
Atomistry »
  Chlorine »
    PDB 3lcd-3lnr »
      3lj7 »

Chlorine in PDB 3lj7: 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597

Protein crystallography data

The structure of 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597, PDB code: 3lj7 was solved by M.Mileni, R.C.Stevens, S.Kamtekar, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.80 / 2.30
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 102.733, 105.075, 147.802, 90.00, 90.00, 90.00
R / Rfree (%) 17.6 / 21.4

Chlorine Binding Sites:

The binding sites of Chlorine atom in the 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597 (pdb code 3lj7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597, PDB code: 3lj7:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 3lj7

Go back to Chlorine Binding Sites List in 3lj7
Chlorine binding site 1 out of 2 in the 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl580

b:42.3
occ:1.00
O B:HOH777 3.1 55.0 1.0
O A:HOH714 3.2 50.6 1.0
ND2 A:ASN259 3.5 40.7 1.0
ND2 B:ASN259 3.6 47.4 1.0
CZ2 B:TRP556 3.8 30.3 1.0
CZ2 A:TRP556 3.9 26.5 1.0
CH2 B:TRP556 4.0 28.1 1.0
CH2 A:TRP556 4.1 33.4 1.0
CB B:ASN259 4.3 33.6 1.0
CB A:ASN259 4.3 36.7 1.0
CG A:ASN259 4.4 45.9 1.0
CG B:ASN259 4.5 44.3 1.0
CG A:PRO310 4.6 37.2 1.0
CD A:PRO310 4.7 32.5 1.0
CD B:PRO310 4.8 36.6 1.0
CG B:PRO310 4.8 35.0 1.0
O A:HOH620 4.9 44.1 1.0

Chlorine binding site 2 out of 2 in 3lj7

Go back to Chlorine Binding Sites List in 3lj7
Chlorine binding site 2 out of 2 in the 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of 3D-Crystal Structure of Humanized-Rat Fatty Acid Amide Hydrolase (Faah) Conjugated with Carbamate Inhibitor URB597 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl2

b:60.6
occ:1.00
N A:GLN35 3.3 47.1 1.0
O A:HOH721 3.4 48.8 1.0
CB A:GLN35 3.5 43.8 1.0
N A:ARG34 3.6 74.7 1.0
C A:GLY33 3.7 74.7 1.0
CA A:GLY33 3.8 67.7 1.0
CA A:GLN35 4.0 41.3 1.0
C A:ARG34 4.4 56.4 1.0
O A:GLY33 4.4 69.3 1.0
CA A:ARG34 4.5 68.2 1.0
CG A:GLN35 4.8 53.9 1.0
N A:GLY33 4.8 60.6 1.0

Reference:

M.Mileni, S.Kamtekar, D.C.Wood, T.E.Benson, B.F.Cravatt, R.C.Stevens. Crystal Structure of Fatty Acid Amide Hydrolase Bound to the Carbamate Inhibitor URB597: Discovery of A Deacylating Water Molecule and Insight Into Enzyme Inactivation J.Mol.Biol. V. 400 743 2010.
ISSN: ISSN 0022-2836
PubMed: 20493882
DOI: 10.1016/J.JMB.2010.05.034
Page generated: Fri Jul 11 07:28:18 2025

Last articles

Cl in 4A0P
Cl in 3ZZH
Cl in 456C
Cl in 3ZZF
Cl in 3ZZW
Cl in 3ZXV
Cl in 3ZXR
Cl in 3ZZE
Cl in 3ZXQ
Cl in 3ZX6
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy