Chlorine in PDB 3lo4: Crystal Structure of Human Alpha-Defensin 1 (R24A Mutant)

The structure of Crystal Structure of Human Alpha-Defensin 1 (R24A Mutant), PDB code: 3lo4 was solved by M.Pazgier, W.Lu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.75
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	46.627, 48.673, 24.557, 90.00, 90.00, 90.00
R / Rfree (%)	17.1 / 21

The binding sites of Chlorine atom in the Crystal Structure of Human Alpha-Defensin 1 (R24A Mutant) (pdb code 3lo4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Alpha-Defensin 1 (R24A Mutant), PDB code: 3lo4:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Alpha-Defensin 1 (R24A Mutant)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Alpha-Defensin 1 (R24A Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl33 b:67.3 occ:1.00 O B:HOH45 2.4 40.0 1.0 O B:PRO7 3.5 22.2 1.0 O B:LEU25 4.0 17.6 1.0 NH1 B:ARG15 4.1 23.0 1.0 N B:ALA27 4.2 17.8 1.0 C B:PRO7 4.3 20.7 1.0 C B:TRP26 4.3 17.9 1.0 CA B:TRP26 4.4 17.3 1.0 NH2 B:ARG15 4.4 19.6 1.0 CA B:PRO7 4.5 20.6 1.0 C B:LEU25 4.5 16.9 1.0 O B:HOH58 4.5 35.6 1.0 O B:HOH50 4.6 33.9 1.0 N B:TRP26 4.6 16.9 1.0 CZ B:ARG15 4.7 20.8 1.0 O B:HOH49 4.8 25.6 1.0 O B:TRP26 4.9 18.4 1.0 O B:ARG5 5.0 19.3 1.0 CA B:ALA27 5.0 18.2 1.0

G.Wei, M.Pazgier, E.De Leeuw, M.Rajabi, J.Li, G.Zou, G.Jung, W.Yuan, W.Y.Lu, R.I.Lehrer, W.Lu. Trp-26 Imparts Functional Versatility to Human Alpha-Defensin HNP1. J.Biol.Chem. V. 285 16275 2010.
ISSN: ISSN 0021-9258
PubMed: 20220136
DOI: 10.1074/JBC.M110.102749