Chlorine in PDB 3m6z: Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride

The structure of Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride, PDB code: 3m6z was solved by R.Rajan, B.Taneja, A.Mondragon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.90 / 1.40
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	63.640, 80.110, 137.220, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 18.4

The structure of Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Chlorine atom in the Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride (pdb code 3m6z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride, PDB code: 3m6z:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl386 b:32.5 occ:1.00 N A:ARG14 3.1 15.4 0.5 N A:ARG14 3.1 15.7 0.5 CB A:ARG14 3.5 15.5 0.5 N A:GLU13 3.5 15.4 1.0 CB A:ARG14 3.5 16.1 0.5 CB A:SER12 3.5 14.5 1.0 OG A:SER12 3.7 15.4 1.0 CA A:ARG14 3.9 14.4 0.5 CA A:ARG14 3.9 15.0 0.5 CA A:GLU13 4.0 15.6 1.0 CB A:GLU13 4.0 17.0 1.0 C A:GLU13 4.0 15.5 1.0 O A:HOH633 4.0 22.1 1.0 C A:SER12 4.2 15.1 1.0 CA A:SER12 4.4 14.9 1.0 CG A:ARG14 4.8 16.1 0.5 CG A:ARG14 4.8 16.1 0.5 CD A:ARG14 5.0 18.5 0.5

Chlorine binding site 2 out of 2 in the Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of An N-Terminal 44 kDa Fragment of Topoisomerase V in the Presence of Guanidium Hydrochloride within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl387 b:48.8 occ:1.00 NZ A:LYS116 2.8 20.0 0.5 N A:VAL4 2.9 22.8 1.0 N A:TYR5 3.4 17.0 0.5 N A:TYR5 3.5 15.8 0.5 O A:HOH625 3.6 32.0 1.0 O A:TYR5 3.7 15.7 0.5 CE A:LYS116 3.7 19.3 0.5 CD2 A:TYR5 3.9 12.8 0.5 O A:TYR5 4.0 13.8 0.5 CA A:VAL4 4.1 19.6 1.0 NH2 A:ARG112 4.2 12.5 0.5 CB A:TYR5 4.2 16.4 0.5 CB A:TYR5 4.2 13.3 0.5 CA A:TYR5 4.2 16.3 0.5 C A:VAL4 4.3 17.8 1.0 CA A:TYR5 4.3 14.5 0.5 CD2 A:TYR5 4.3 17.3 0.5 C A:TYR5 4.4 15.9 0.5 CG A:TYR5 4.5 12.5 0.5 C A:TYR5 4.5 14.0 0.5 CG A:TYR5 4.8 16.6 0.5 CE2 A:TYR5 4.8 12.3 0.5

R.Rajan, B.Taneja, A.Mondragon. Structures of Minimal Catalytic Fragments of Topoisomerase V Reveals Conformational Changes Relevant For Dna Binding. Structure V. 18 829 2010.
ISSN: ISSN 0969-2126
PubMed: 20637419
DOI: 10.1016/J.STR.2010.03.006