Chlorine in PDB 3muj: Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices

The structure of Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices, PDB code: 3muj was solved by M.I.Siponen, L.Lehtio, C.H.Arrowsmith, C.Bountra, R.Collins, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, I.Johansson, T.Karlberg, T.Kotenyova, M.Moche, P.Nordlund, T.Nyman, C.Persson, H.Schueler, P.Schutz, L.Svensson, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, E.Wahlberg, J.Weigelt, M.Welin, M.Wisniewska, H.Berglund, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.10 / 1.92
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	134.680, 134.680, 41.150, 90.00, 90.00, 120.00
R / Rfree (%)	17 / 19.3

The binding sites of Chlorine atom in the Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices (pdb code 3muj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices, PDB code: 3muj:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl396 b:56.7 occ:1.00 NH2 A:ARG364 3.0 56.0 1.0 O A:HOH184 3.3 41.3 1.0 NE2 A:GLN352 3.4 29.8 1.0 O A:HOH23 3.5 24.6 1.0 CZ A:ARG364 3.5 57.5 1.0 NH1 A:ARG364 3.5 65.0 1.0 CB A:GLN352 3.8 28.6 1.0 O A:PHE348 3.8 19.7 1.0 CG A:GLN352 4.1 32.0 1.0 NZ A:LYS367 4.1 41.9 1.0 C A:PHE348 4.1 18.9 1.0 CE A:LYS367 4.1 38.2 1.0 CD A:GLN352 4.3 29.1 1.0 CA A:GLN349 4.3 22.9 1.0 CB A:PHE348 4.3 19.5 1.0 N A:GLN349 4.3 19.0 1.0 O A:HOH230 4.3 45.5 1.0 CD1 A:LEU370 4.4 24.3 1.0 NE A:ARG364 4.5 62.7 1.0 CD A:LYS367 4.7 35.5 1.0 CA A:PHE348 4.9 18.8 1.0

Chlorine binding site 2 out of 2 in the Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Early B-Cell Factor 3 (EBF3) Ipt/Tig and Dimerization Helices within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl396 b:54.1 occ:1.00 O B:HOH204 2.7 36.5 1.0 O B:HOH94 3.0 29.4 1.0 NE2 B:HIS358 3.3 27.9 1.0 CB B:ARG373 4.0 15.5 1.0 CE1 B:HIS358 4.0 35.9 1.0 CG B:PRO356 4.0 20.2 1.0 CB B:PRO356 4.0 19.9 1.0 CD B:ARG373 4.1 20.6 1.0 CG B:ARG373 4.1 20.1 1.0 CD B:PRO356 4.4 20.4 1.0 CD2 B:HIS358 4.4 26.6 1.0 CD2 B:LEU377 4.6 16.5 1.0 CG B:LEU377 4.6 13.4 1.0 O B:PRO356 4.7 19.3 1.0 CA B:ARG373 4.8 20.3 1.0 O B:ARG373 4.8 14.8 1.0 NE B:ARG373 4.9 20.1 1.0 CD1 B:LEU377 4.9 15.6 1.0

M.I.Siponen, M.Wisniewska, L.Lehtio, I.Johansson, L.Svensson, G.Raszewski, L.Nilsson, M.Sigvardsson, H.Berglund. Structural Determination of Functional Domains in Early B-Cell Factor (Ebf) Family of Transcription Factors Reveals Similarities to Rel Dna-Binding Proteins and A Novel Dimerization Motif. J.Biol.Chem. V. 285 25875 2010.
ISSN: ISSN 0021-9258
PubMed: 20592035
DOI: 10.1074/JBC.C110.150482