Chlorine in PDB 3mws: Crystal Structure of Group N Hiv-1 Protease

All present enzymatic activity of Crystal Structure of Group N Hiv-1 Protease:
3.4.23.16;

The structure of Crystal Structure of Group N Hiv-1 Protease, PDB code: 3mws was solved by J.M.Sayer, J.Agniswamy, I.T.Weber, J.M.Louis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.09
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.940, 53.372, 66.086, 90.00, 90.00, 90.00
R / Rfree (%)	16.7 / 21.7

The binding sites of Chlorine atom in the Crystal Structure of Group N Hiv-1 Protease (pdb code 3mws). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Group N Hiv-1 Protease, PDB code: 3mws:

Chlorine binding site 1 out of 1 in the Crystal Structure of Group N Hiv-1 Protease


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Group N Hiv-1 Protease within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:11.6 occ:1.00 O A:HOH1019 3.1 19.0 1.0 N A:GLU21 3.1 7.1 1.0 CA A:ARG20 3.6 8.1 0.7 CA A:ARG20 3.6 8.3 0.3 CD A:ARG20 3.7 12.1 0.7 CG A:GLU21 3.8 10.1 1.0 CB A:ARG20 3.8 9.3 0.7 C A:ARG20 3.9 7.5 1.0 CB A:ARG20 3.9 9.5 0.3 CD A:ARG20 3.9 11.8 0.3 NE A:ARG20 3.9 13.4 0.3 ND2 A:ASN83 4.0 10.9 1.0 O A:GLU21 4.2 8.4 1.0 CA A:GLU21 4.2 7.8 1.0 CB A:GLU21 4.3 9.2 1.0 CG A:ARG20 4.4 10.3 0.7 CG A:ARG20 4.5 9.8 0.3 C A:GLU21 4.7 6.8 1.0 CD A:GLU21 4.7 8.5 1.0 O A:VAL19 4.9 12.6 1.0 N A:ARG20 4.9 8.8 1.0 NE A:ARG20 5.0 9.7 0.7

J.M.Sayer, J.Agniswamy, I.T.Weber, J.M.Louis. Autocatalytic Maturation, Physical/Chemical Properties, and Crystal Structure of Group N Hiv-1 Protease: Relevance to Drug Resistance. Protein Sci. V. 19 2055 2010.
ISSN: ISSN 0961-8368
PubMed: 20737578
DOI: 10.1002/PRO.486