Chlorine in PDB 3n5c: Crystal Structure of ARF6DELTA13 Complexed with Gdp

The structure of Crystal Structure of ARF6DELTA13 Complexed with Gdp, PDB code: 3n5c was solved by K.Aizel, V.Biou, J.Cherfils, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.83 / 1.82
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.470, 49.720, 143.070, 90.00, 90.00, 90.00
R / Rfree (%)	17.1 / 19.5

The binding sites of Chlorine atom in the Crystal Structure of ARF6DELTA13 Complexed with Gdp (pdb code 3n5c). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of ARF6DELTA13 Complexed with Gdp, PDB code: 3n5c:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of ARF6DELTA13 Complexed with Gdp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of ARF6DELTA13 Complexed with Gdp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:28.5 occ:1.00 OH A:TYR78 3.0 24.7 1.0 NH1 A:ARG105 3.1 32.4 1.0 N A:HIS76 3.2 20.6 1.0 NH2 A:ARG105 3.3 31.7 1.0 CZ A:ARG105 3.7 37.9 1.0 CA A:ARG75 3.7 22.6 1.0 CB A:ARG75 3.7 23.5 1.0 CE1 A:TYR78 3.7 19.2 1.0 CZ A:TYR78 3.8 22.2 1.0 ND1 A:HIS76 3.8 26.4 1.0 CD A:ARG71 4.0 39.9 1.0 C A:ARG75 4.0 24.3 1.0 CB A:HIS76 4.1 20.7 1.0 CA A:HIS76 4.2 20.2 1.0 CG A:ARG75 4.2 29.8 1.0 O A:HIS76 4.2 20.7 1.0 CZ A:ARG75 4.3 50.4 1.0 NH2 A:ARG75 4.3 31.8 1.0 NE A:ARG75 4.4 43.6 1.0 NE A:ARG71 4.4 42.0 1.0 CG A:HIS76 4.4 24.0 1.0 NH1 A:ARG71 4.5 42.7 1.0 CZ A:ARG71 4.6 53.3 1.0 C A:HIS76 4.6 21.2 1.0 NH1 A:ARG75 4.7 37.2 1.0 O A:HOH195 4.7 28.4 1.0 O A:HOH12 4.9 25.3 1.0 CG A:ARG71 4.9 35.1 1.0 CE1 A:HIS76 4.9 24.8 1.0 CD A:ARG75 4.9 32.1 1.0 NE A:ARG105 5.0 29.8 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of ARF6DELTA13 Complexed with Gdp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of ARF6DELTA13 Complexed with Gdp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl180 b:50.9 occ:1.00 NH1 A:ARG75 3.2 37.2 1.0 NH2 A:ARG71 3.4 36.9 1.0 NH1 A:ARG71 3.4 42.7 1.0 CD A:ARG75 3.8 32.1 1.0 CG A:ARG75 3.8 29.8 1.0 CZ A:ARG71 3.9 53.3 1.0 CZ A:ARG75 4.3 50.4 1.0 O A:HOH236 4.4 40.6 1.0 NE A:ARG75 4.5 43.6 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of ARF6DELTA13 Complexed with Gdp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of ARF6DELTA13 Complexed with Gdp within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2 b:30.7 occ:1.00 OH B:TYR78 3.0 22.4 1.0 NH2 B:ARG105 3.1 50.5 1.0 N B:HIS76 3.3 18.9 1.0 NE B:ARG105 3.5 47.6 1.0 CZ B:ARG105 3.7 61.5 1.0 CA B:ARG75 3.8 18.7 1.0 CD2 B:HIS76 3.9 23.6 1.0 CB B:ARG75 3.9 20.9 1.0 CZ B:TYR78 3.9 23.0 1.0 CE1 B:TYR78 4.0 22.4 1.0 CB B:HIS76 4.0 18.7 1.0 C B:ARG75 4.1 20.8 1.0 CG B:ARG75 4.1 33.1 1.0 CA B:HIS76 4.2 16.9 1.0 CG B:HIS76 4.3 21.8 1.0 CZ B:ARG75 4.3 82.6 1.0 NE B:ARG75 4.4 66.6 1.0 O B:HOH241 4.4 35.6 1.0 NH1 B:ARG71 4.4 45.0 1.0 NH2 B:ARG75 4.4 70.9 1.0 O B:HIS76 4.4 21.1 1.0 CD B:ARG71 4.7 37.4 1.0 NH1 B:ARG75 4.7 66.3 1.0 CD B:ARG105 4.7 51.4 1.0 C B:HIS76 4.8 19.7 1.0 CD B:ARG75 4.9 49.9 1.0 CZ B:ARG71 4.9 55.7 1.0

V.Biou, K.Aizel, P.Roblin, A.Thureau, E.Jacquet, S.Hansson, B.Guibert, E.Guittet, C.Van Heijenoort, M.Zeghouf, J.Perez, J.Cherfils. Saxs and X-Ray Crystallography Suggest An Unfolding Model For the Gdp/Gtp Conformational Switch of the Small Gtpase ARF6. J.Mol.Biol. V. 402 696 2010.
ISSN: ISSN 0022-2836
PubMed: 20709080
DOI: 10.1016/J.JMB.2010.08.002