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Chlorine in PDB 3nv8: The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free)

Enzymatic activity of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free)

All present enzymatic activity of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free):
2.5.1.54;

Protein crystallography data

The structure of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free), PDB code: 3nv8 was solved by E.J.Parker, G.B.Jameson, W.Jiao, R.H.Hutton, C.J.Webby, E.N.Baker, H.M.Baker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.37 / 2.25
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 203.538, 203.538, 66.422, 90.00, 90.00, 120.00
R / Rfree (%) 18 / 20.8

Other elements in 3nv8:

The structure of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free) also contains other interesting chemical elements:

Manganese (Mn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free) (pdb code 3nv8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free), PDB code: 3nv8:

Chlorine binding site 1 out of 1 in 3nv8

Go back to Chlorine Binding Sites List in 3nv8
Chlorine binding site 1 out of 1 in the The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase in Complex with Phosphoenol Pyruvate and Manganese (Thesit-Free) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl470

b:71.2
occ:1.00
O B:HOH612 2.6 49.1 1.0
O B:HOH504 2.6 59.6 1.0
NH2 B:ARG49 3.0 41.1 1.0
NH2 B:ARG256 3.7 35.2 1.0
CZ B:ARG49 3.9 37.0 1.0
NH1 B:ARG49 4.2 43.1 1.0
NH1 B:ARG256 4.4 37.5 1.0
CZ B:ARG256 4.5 37.1 1.0
NE B:ARG49 4.9 30.0 1.0

Reference:

C.J.Webby, W.Jiao, R.D.Hutton, N.J.Blackmore, H.M.Baker, E.N.Baker, G.B.Jameson, E.J.Parker. Synergistic Allostery, A Sophisticated Regulatory Network For the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium Tuberculosis J.Biol.Chem. V. 285 30567 2010.
ISSN: ISSN 0021-9258
PubMed: 20667835
DOI: 10.1074/JBC.M110.111856
Page generated: Sat Dec 12 09:58:24 2020

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