Chlorine in PDB 3o0g: Crystal Structure of CDK5:P25 in Complex with An Atp Analogue

All present enzymatic activity of Crystal Structure of CDK5:P25 in Complex with An Atp Analogue:
2.7.11.22;

The structure of Crystal Structure of CDK5:P25 in Complex with An Atp Analogue, PDB code: 3o0g was solved by M.Mapelli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.96 / 1.95
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	117.124, 117.124, 155.599, 90.00, 90.00, 120.00
R / Rfree (%)	22.6 / 25.6

The binding sites of Chlorine atom in the Crystal Structure of CDK5:P25 in Complex with An Atp Analogue (pdb code 3o0g). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of CDK5:P25 in Complex with An Atp Analogue, PDB code: 3o0g:

Chlorine binding site 1 out of 1 in the Crystal Structure of CDK5:P25 in Complex with An Atp Analogue


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of CDK5:P25 in Complex with An Atp Analogue within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl293 b:55.1 occ:1.00 CLA B:3O0293 0.0 55.1 1.0 CAL B:3O0293 1.7 50.2 1.0 CAK B:3O0293 2.7 52.2 1.0 CAV B:3O0293 2.7 46.5 1.0 CD B:LYS89 3.8 46.0 1.0 CAJ B:3O0293 4.0 51.0 1.0 CAU B:3O0293 4.0 43.9 1.0 CB B:LYS89 4.2 40.2 1.0 OD2 B:ASP86 4.3 46.0 1.0 N B:ASP86 4.4 42.1 1.0 CG B:ASP86 4.4 42.3 1.0 CG B:LYS89 4.5 42.3 1.0 OD1 B:ASP86 4.5 44.6 1.0 CAT B:3O0293 4.5 46.5 1.0 CA B:GLN85 4.6 45.5 1.0 CB B:GLN85 4.8 45.6 1.0 CE B:LYS89 5.0 47.2 1.0 C B:GLN85 5.0 43.4 1.0

J.S.Ahn, M.L.Radhakrishnan, M.Mapelli, S.Choi, B.Tidor, G.D.Cuny, A.Musacchio, L.Yeh, S.K.Kosik. Defining CDK5 Ligand Chemical Space with Small Molecule Inhibitors of Tau Phosphorylation Chem.Biol. V. 12 811 2005.
ISSN: ISSN 1074-5521
PubMed: 16039528
DOI: 10.1016/J.CHEMBIOL.2005.05.011