Chlorine in PDB 3o24: Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus

The structure of Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus, PDB code: 3o24 was solved by M.Jost, G.E.Zocher, T.Stehle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.50
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	82.850, 82.850, 121.760, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 23.6

The binding sites of Chlorine atom in the Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus (pdb code 3o24). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus, PDB code: 3o24:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl477 b:52.5 occ:0.50 N A:LYS165 3.7 53.6 1.0 CG A:LYS165 3.7 57.9 1.0 CB A:LYS165 4.1 57.6 1.0 CB A:THR164 4.1 52.3 1.0 CA A:THR164 4.3 49.9 1.0 C A:THR164 4.5 52.7 1.0 CA A:LYS165 4.6 55.3 1.0 CG2 A:THR164 4.8 50.2 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl478 b:42.2 occ:0.50 N A:VAL55 3.6 42.3 1.0 CG2 A:VAL55 3.9 43.2 1.0 CA A:ASP54 4.0 41.3 1.0 CB A:ASP54 4.2 44.9 1.0 OD1 A:ASP54 4.3 49.5 1.0 C A:ASP54 4.4 42.9 1.0 CB A:VAL55 4.4 41.5 1.0 CG A:ASP54 4.5 47.6 1.0 CA A:VAL55 4.6 40.8 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl479 b:75.2 occ:1.00 NH1 A:ARG215 4.0 64.6 1.0 NH2 A:ARG215 4.1 62.3 1.0 CG2 A:THR213 4.5 56.5 1.0 CZ A:ARG215 4.6 63.1 1.0 OE2 A:GLU167 4.7 50.8 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the Brevianamide F Prenyltransferase FTMPT1 From Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl480 b:76.5 occ:1.00 N A:ASN389 3.9 56.6 1.0 CA A:MET388 4.1 55.4 1.0 CB A:MET388 4.3 55.3 1.0 C A:MET388 4.5 54.4 1.0 CG A:MET388 4.6 55.7 1.0 CD A:LYS392 4.7 65.7 1.0 CB A:ASN389 4.8 57.1 1.0 CE A:MET388 4.9 59.0 1.0 O A:GLY387 5.0 55.5 1.0 CA A:ASN389 5.0 56.0 1.0

M.Jost, G.Zocher, S.Tarcz, M.Matuschek, X.Xie, S.M.Li, T.Stehle. Structure-Function Analysis of An Enzymatic Prenyl Transfer Reaction Identifies A Reaction Chamber with Modifiable Specificity. J.Am.Chem.Soc. V. 132 17849 2010.
ISSN: ISSN 0002-7863
PubMed: 21105662
DOI: 10.1021/JA106817C