Chlorine in PDB 3o5z: Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K)

The structure of Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K), PDB code: 3o5z was solved by S.Chen, Y.Xiao, R.Ponnusamy, J.Tan, J.Lei, R.Hilgenfeld, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	21.37 / 2.01
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.010, 57.790, 62.970, 90.00, 90.00, 90.00
R / Rfree (%)	21.2 / 25.9

The binding sites of Chlorine atom in the Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K) (pdb code 3o5z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K), PDB code: 3o5z:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl86 b:72.5 occ:1.00 O A:GLU18 4.1 59.4 1.0 NH2 A:ARG17 4.4 72.4 1.0 C A:GLU18 4.5 55.3 1.0 C A:ARG19 4.6 55.3 1.0 O A:ARG19 4.7 54.8 1.0 NH1 A:ARG17 4.7 70.5 1.0 N A:PRO20 4.7 59.0 1.0 CZ A:ARG17 4.8 68.0 1.0 N A:ARG19 4.9 53.4 1.0 CA A:ARG19 5.0 55.0 1.0 O A:ARG17 5.0 55.1 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the SH3 Domain From P85BETA Subunit of Phosphoinositide 3-Kinase (PI3K) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl86 b:57.7 occ:1.00 OE2 B:GLU21 4.2 88.6 1.0 OD2 A:ASP69 4.4 51.3 1.0 OD2 B:ASP69 4.7 56.2 1.0 CD B:GLU21 4.8 84.1 1.0

S.Chen, Y.Xiao, R.Ponnusamy, J.Tan, J.Lei, R.Hilgenfeld. X-Ray Structure of the SH3 Domain of the Phosphoinositide 3-Kinase P85 Beta Subunit Acta Crystallogr.,Sect.F V. 67 1328 2011.
ISSN: ISSN 1744-3091
PubMed: 22102226
DOI: 10.1107/S1744309111031691