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Chlorine in PDB 3ofm: Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens

Enzymatic activity of Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens

All present enzymatic activity of Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens:
2.7.11.1;

Protein crystallography data

The structure of Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens, PDB code: 3ofm was solved by N.Bischoff, B.Olsen, J.Raaf, M.Bretner, O.-G.Issinger, K.Niefind, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 33.03 / 2.00
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 46.690, 47.570, 50.570, 112.40, 89.49, 91.30
R / Rfree (%) 17.2 / 20.7

Other elements in 3ofm:

The structure of Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens also contains other interesting chemical elements:

Bromine (Br) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens (pdb code 3ofm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens, PDB code: 3ofm:

Chlorine binding site 1 out of 1 in 3ofm

Go back to Chlorine Binding Sites List in 3ofm
Chlorine binding site 1 out of 1 in the Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of A Human CK2ALPHA Prime, the Paralog Isoform of the Catalytic Subunit of Protein Kinase CK2 From Homo Sapiens within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl352

b:36.7
occ:1.00
NH1 A:ARG156 3.2 26.1 1.0
N A:ASN190 3.3 28.1 1.0
O A:HOH550 3.4 35.6 1.0
O A:HOH447 3.7 38.1 1.0
CD1 A:TYR189 3.8 24.4 1.0
CB A:ASN190 3.8 29.4 1.0
NH2 A:ARG156 3.9 20.0 1.0
CA A:TYR189 3.9 26.6 1.0
CZ A:ARG156 4.0 23.7 1.0
CB A:TYR189 4.0 26.4 1.0
C A:TYR189 4.2 27.0 1.0
CA A:ASN190 4.2 29.2 1.0
CG A:TYR189 4.4 24.2 1.0
OE1 A:GLU181 4.6 31.5 1.0
CG A:GLU181 4.7 31.8 1.0
O A:ASN190 4.7 26.7 1.0
CE1 A:TYR189 4.8 25.1 1.0
OH A:TYR210 4.9 23.5 1.0

Reference:

N.Bischoff, B.Olsen, J.Raaf, M.Bretner, O.G.Issinger, K.Niefind. Structural Basis of the Reduced Affinity Between the Protein Kinase CK2 Subunits CK2ALPHA Prime and CK2BETA J.Mol.Biol. V. 407 1 2011.
ISSN: ISSN 0022-2836
PubMed: 21241709
DOI: 10.1016/J.JMB.2011.01.020
Page generated: Sun Jul 21 01:37:54 2024

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