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Atomistry » Chlorine » PDB 3oht-3ook » 3oni » |
Chlorine in PDB 3oni: Crystal Structure of the Second Bromodomain of Human BRD2 in Complex with the Inhibitor JQ1Protein crystallography data
The structure of Crystal Structure of the Second Bromodomain of Human BRD2 in Complex with the Inhibitor JQ1, PDB code: 3oni
was solved by
P.Filippakopoulos,
S.Picaud,
O.Fedorov,
F.Von Delft,
C.H.Arrowsmith,
A.M.Edwards,
J.Weigelt,
C.Bountra,
J.E.Bradner,
Structural Genomicsconsortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3oni:
The structure of Crystal Structure of the Second Bromodomain of Human BRD2 in Complex with the Inhibitor JQ1 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Second Bromodomain of Human BRD2 in Complex with the Inhibitor JQ1
(pdb code 3oni). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Second Bromodomain of Human BRD2 in Complex with the Inhibitor JQ1, PDB code: 3oni: Chlorine binding site 1 out of 1 in 3oniGo back to Chlorine Binding Sites List in 3oni
Chlorine binding site 1 out
of 1 in the Crystal Structure of the Second Bromodomain of Human BRD2 in Complex with the Inhibitor JQ1
Mono view Stereo pair view
Reference:
P.Filippakopoulos,
J.Qi,
S.Picaud,
Y.Shen,
W.B.Smith,
O.Fedorov,
E.M.Morse,
T.Keates,
T.T.Hickman,
I.Felletar,
M.Philpott,
S.Munro,
M.R.Mckeown,
Y.Wang,
A.L.Christie,
N.West,
M.J.Cameron,
B.Schwartz,
T.D.Heightman,
N.La Thangue,
C.A.French,
O.Wiest,
A.L.Kung,
S.Knapp,
J.E.Bradner.
Selective Inhibition of Bet Bromodomains. Nature V. 468 1067 2010.
Page generated: Sat Dec 12 10:00:21 2020
ISSN: ISSN 0028-0836 PubMed: 20871596 DOI: 10.1038/NATURE09504 |
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