Chlorine in PDB 3ose: Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase

All present enzymatic activity of Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase:
2.7.11.1;

The structure of Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase, PDB code: 3ose was solved by K.Moravcevic, M.A.Lemmon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 1.70
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	69.843, 69.843, 54.446, 90.00, 90.00, 120.00
R / Rfree (%)	17.5 / 19.5

The binding sites of Chlorine atom in the Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase (pdb code 3ose). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase, PDB code: 3ose:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl796 b:12.7 occ:1.00 N A:TRP704 3.3 12.2 1.0 CA A:THR703 3.8 11.7 1.0 CB A:THR703 3.8 12.1 1.0 CB A:TRP704 3.9 13.1 1.0 C A:THR703 4.0 12.1 1.0 CA A:TRP704 4.2 13.7 1.0 O A:HOH51 4.2 27.3 1.0 CG2 A:THR703 4.4 13.1 1.0

Chlorine binding site 2 out of 2 in the Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Kinase Associated Domain 1 (KA1) From MARK1 Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl797 b:23.9 occ:1.00 O A:HOH17 2.9 23.2 1.0 O A:HOH86 3.2 31.9 1.0 OG A:SER705 3.3 19.0 1.0 O A:SER705 3.4 18.7 1.0 CA A:ARG771 3.5 8.8 1.0 N A:PHE772 3.6 8.3 1.0 C A:SER705 3.6 17.0 1.0 NZ A:LYS707 3.6 15.6 1.0 CB A:SER705 3.7 16.9 1.0 CG A:ARG771 3.7 12.2 1.0 N A:MET706 3.8 15.9 1.0 CA A:MET706 4.0 15.7 1.0 CB A:ARG771 4.0 9.2 1.0 O A:PHE772 4.0 10.3 1.0 C A:ARG771 4.1 8.7 1.0 CE A:MET706 4.1 14.9 1.0 CA A:SER705 4.3 16.9 1.0 O A:VAL770 4.3 9.2 1.0 CB A:MET706 4.6 15.0 1.0 N A:ARG771 4.6 8.6 1.0 CA A:PHE772 4.7 8.5 1.0 C A:PHE772 4.8 9.3 1.0 SD A:MET706 4.9 14.2 1.0 O A:HOH16 4.9 18.0 1.0 C A:VAL770 4.9 8.3 1.0 CD A:ARG771 4.9 14.2 1.0

K.Moravcevic, J.M.Mendrola, K.R.Schmitz, Y.H.Wang, D.Slochower, P.A.Janmey, M.A.Lemmon. Kinase Associated-1 Domains Drive Mark/PAR1 Kinases to Membrane Targets By Binding Acidic Phospholipids. Cell(Cambridge,Mass.) V. 143 966 2010.
ISSN: ISSN 0092-8674
PubMed: 21145462
DOI: 10.1016/J.CELL.2010.11.028