Atomistry » Chlorine » PDB 3oow-3owv » 3owk
Atomistry »
  Chlorine »
    PDB 3oow-3owv »
      3owk »

Chlorine in PDB 3owk: Human CK2 Catalytic Domain in Complex with A Benzopyridoindole Derivative Inhibitor

Protein crystallography data

The structure of Human CK2 Catalytic Domain in Complex with A Benzopyridoindole Derivative Inhibitor, PDB code: 3owk was solved by J.-B.Reiser, R.Prudent, C.Cochet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.12 / 1.80
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 58.489, 46.362, 63.942, 90.00, 111.47, 90.00
R / Rfree (%) 21.9 / 26.2

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human CK2 Catalytic Domain in Complex with A Benzopyridoindole Derivative Inhibitor (pdb code 3owk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human CK2 Catalytic Domain in Complex with A Benzopyridoindole Derivative Inhibitor, PDB code: 3owk:

Chlorine binding site 1 out of 1 in 3owk

Go back to Chlorine Binding Sites List in 3owk
Chlorine binding site 1 out of 1 in the Human CK2 Catalytic Domain in Complex with A Benzopyridoindole Derivative Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human CK2 Catalytic Domain in Complex with A Benzopyridoindole Derivative Inhibitor within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl332

b:42.9
occ:1.00
CL18 A:18E332 0.0 42.9 1.0
C18 A:18E332 1.8 36.0 1.0
N17 A:18E332 2.7 34.9 1.0
C13 A:18E332 2.8 33.8 1.0
O A:HOH369 3.0 24.2 1.0
CZ A:PHE113 3.3 21.9 1.0
C9 A:18E332 3.3 33.6 1.0
CE2 A:PHE113 3.4 21.3 1.0
C8 A:18E332 3.4 33.6 1.0
N A:ASP175 3.5 17.4 1.0
NZ A:LYS68 3.7 26.2 1.0
CA A:ASP175 3.8 18.1 1.0
CE1 A:PHE113 3.8 21.4 1.0
CE A:LYS68 3.9 26.8 1.0
CD2 A:PHE113 4.0 21.1 1.0
C16 A:18E332 4.0 34.5 1.0
C12 A:18E332 4.2 33.5 1.0
CB A:ILE174 4.3 16.5 1.0
CD1 A:PHE113 4.4 21.3 1.0
CG A:PHE113 4.4 22.8 1.0
CD A:LYS68 4.5 26.6 1.0
CB A:ASP175 4.5 18.3 1.0
C A:ILE174 4.6 16.9 1.0
C14 A:18E332 4.7 34.5 1.0
C10 A:18E332 4.7 32.6 1.0
OE2 A:GLU81 4.7 26.4 1.0
CA A:ILE174 4.8 16.4 1.0
N A:TRP176 4.8 18.1 1.0
C7 A:18E332 4.8 33.0 1.0
C A:ASP175 4.9 18.3 1.0
CG2 A:ILE95 4.9 17.9 1.0

Reference:

R.Prudent, V.Moucadel, C.H.Nguyen, C.Barette, F.Schmidt, J.C.Florent, L.Lafanechere, C.F.Sautel, E.Duchemin-Pelletier, E.Spreux, O.Filhol, J.B.Reiser, C.Cochet. Antitumor Activity of Pyridocarbazole and Benzopyridoindole Derivatives That Inhibit Protein Kinase CK2. Cancer Res. V. 70 9865 2010.
ISSN: ISSN 0008-5472
PubMed: 21118972
DOI: 10.1158/0008-5472.CAN-10-0917
Page generated: Sat Dec 12 10:01:00 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy