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Atomistry » Chlorine » PDB 3oxh-3p41 » 3p0q » |
Chlorine in PDB 3p0q: Human Tankyrase 2 - Catalytic Parp Domain in Complex with An InhibitorEnzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
All present enzymatic activity of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor:
2.4.2.30; Protein crystallography data
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0q
was solved by
T.Karlberg,
M.I.Siponen,
C.H.Arrowsmith,
H.Berglund,
C.Bountra,
R.Collins,
A.M.Edwards,
S.Flodin,
A.Flores,
S.Graslund,
M.Hammarstrom,
I.Johansson,
T.Kotenyova,
E.Kouznetsova,
M.Moche,
P.Nordlund,
T.Nyman,
C.Persson,
P.Schutz,
A.Sehic,
A.G.Thorsell,
L.Tresaugues,
S.Van Den Berg,
E.Wahlberg,
J.Weigelt,
M.Welin,
H.Schuler,
Structural Genomicsconsortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3p0q:
The structure of Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
(pdb code 3p0q). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor, PDB code: 3p0q: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 3p0qGo back to Chlorine Binding Sites List in 3p0q
Chlorine binding site 1 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 3p0qGo back to Chlorine Binding Sites List in 3p0q
Chlorine binding site 2 out
of 2 in the Human Tankyrase 2 - Catalytic Parp Domain in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
E.Wahlberg,
T.Karlberg,
E.Kouznetsova,
N.Markova,
A.Macchiarulo,
A.G.Thorsell,
E.Pol,
A.Frostell,
T.Ekblad,
B.Kull,
G.M.Robertson,
R.Pellicciari,
H.Schuler,
J.Weigelt.
Family-Wide Chemical Profiling and Structural Analysis of Parp and Tankyrase Inhibitors Nat.Biotechnol. V. 30 283 2012.
Page generated: Sat Dec 12 10:01:25 2020
ISSN: ISSN 1087-0156 PubMed: 22343925 DOI: 10.1038/NBT.2121 |
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