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Atomistry » Chlorine » PDB 3qck-3qoo » 3qk0 » |
Chlorine in PDB 3qk0: Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82Enzymatic activity of Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82
All present enzymatic activity of Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82:
2.7.1.153; Protein crystallography data
The structure of Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82, PDB code: 3qk0
was solved by
D.A.Whittington,
J.Tang,
P.Yakowec,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3qk0:
The structure of Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82
(pdb code 3qk0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82, PDB code: 3qk0: Chlorine binding site 1 out of 1 in 3qk0Go back to Chlorine Binding Sites List in 3qk0
Chlorine binding site 1 out
of 1 in the Crystal Structure of PI3K-Gamma in Complex with Benzothiazole 82
Mono view Stereo pair view
Reference:
N.D.D'angelo,
T.S.Kim,
K.Andrews,
S.K.Booker,
S.Caenepeel,
K.Chen,
D.D'amico,
D.Freeman,
J.Jiang,
L.Liu,
J.D.Mccarter,
T.San Miguel,
E.L.Mullady,
M.Schrag,
R.Subramanian,
J.Tang,
R.C.Wahl,
L.Wang,
D.A.Whittington,
T.Wu,
N.Xi,
Y.Xu,
P.Yakowec,
K.Yang,
L.P.Zalameda,
N.Zhang,
P.Hughes,
M.H.Norman.
Discovery and Optimization of A Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (Mtor) Dual Inhibitors. J.Med.Chem. V. 54 1789 2011.
Page generated: Sat Dec 12 10:04:37 2020
ISSN: ISSN 0022-2623 PubMed: 21332118 DOI: 10.1021/JM1014605 |
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