Chlorine in PDB 3rco: Crystal Structure of A Conserved Motif in Human TDRD7

The structure of Crystal Structure of A Conserved Motif in Human TDRD7, PDB code: 3rco was solved by A.Dong, C.Xu, J.R.Walker, R.Lam, Y.Guo, C.Bian, Y.Li, C.Bountra, J.Weigelt, C.H.Arrowsmith, A.M.Edwards, J.Min, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.80
Space group	I 2 3
Cell size a, b, c (Å), α, β, γ (°)	99.788, 99.788, 99.788, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 23

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 11;

Binding sites:

The binding sites of Chlorine atom in the Crystal Structure of A Conserved Motif in Human TDRD7 (pdb code 3rco). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 11 binding sites of Chlorine where determined in the Crystal Structure of A Conserved Motif in Human TDRD7, PDB code: 3rco:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2 b:19.1 occ:1.00 O A:HOH102 3.1 13.9 0.3 N A:GLN60 3.2 20.4 1.0 C A:PRO57 3.3 14.1 1.0 CA A:PRO57 3.3 13.6 1.0 N A:LYS59 3.3 17.2 1.0 CB A:LYS59 3.5 20.3 1.0 CG A:GLN60 3.6 18.9 1.0 O A:PRO57 3.7 15.2 1.0 N A:PHE58 3.7 13.3 1.0 CA A:LYS59 3.7 19.8 1.0 CB A:PRO57 3.9 14.4 1.0 C A:LYS59 4.0 20.9 1.0 CB A:GLN60 4.1 21.1 1.0 CG A:LYS59 4.2 23.8 1.0 CA A:GLN60 4.3 20.6 1.0 C A:PHE58 4.3 16.7 1.0 CD A:GLN60 4.5 20.1 1.0 CA A:PHE58 4.6 14.0 1.0 N A:PRO57 4.7 12.1 1.0 O A:ILE56 4.8 13.2 1.0 OE1 A:GLN60 4.8 25.2 1.0 O A:HOH100 4.9 29.1 1.0

Chlorine binding site 2 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl3 b:23.0 occ:1.00 O A:HOH101 3.0 38.4 1.0 O A:HOH116 3.1 19.4 1.0 N A:GLU67 3.3 14.0 1.0 N A:LEU66 3.8 14.5 1.0 CB A:GLU67 3.8 13.4 1.0 CB A:LEU66 3.9 12.1 1.0 CB A:THR65 3.9 19.2 1.0 CA A:GLU67 4.2 15.1 1.0 CD2 A:LEU41 4.2 25.6 1.0 CA A:LEU66 4.2 12.4 1.0 C A:LEU66 4.2 14.2 1.0 OG1 A:THR65 4.3 18.1 1.0 C A:THR65 4.6 15.2 1.0 CA A:THR65 4.7 17.6 1.0 CG A:LEU41 4.8 17.6 1.0 CG A:LEU66 4.8 14.0 1.0 CG2 A:THR65 4.9 21.2 1.0

Chlorine binding site 3 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl6 b:27.8 occ:1.00 N A:ILE87 3.0 13.3 1.0 OE1 A:GLU86 3.3 25.9 0.5 O A:HOH129 3.3 29.8 1.0 CD A:PRO42 3.4 19.3 1.0 CG A:PRO42 3.6 21.0 1.0 CB A:ILE87 3.6 14.5 1.0 CA A:ILE87 3.8 13.2 1.0 CA A:GLU86 3.8 10.0 0.5 CG1 A:ILE87 3.8 14.1 1.0 C A:GLU86 3.8 9.4 0.5 CD1 A:ILE87 3.9 16.8 1.0 O A:ILE87 4.0 15.6 1.0 CB A:LEU41 4.3 16.5 1.0 O A:GLY85 4.3 14.3 1.0 C A:ILE87 4.4 15.0 1.0 CD A:GLU86 4.4 20.9 0.5 CB A:GLU86 4.5 11.3 0.5 N A:PRO42 4.6 18.7 1.0 N A:LEU41 4.7 17.2 1.0 CA A:LEU41 5.0 17.6 1.0 N A:GLU86 5.0 9.7 0.5

Chlorine binding site 4 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1 b:18.2 occ:1.00 O B:HOH128 3.1 29.8 1.0 N B:ILE87 3.3 9.6 1.0 CD B:PRO42 3.6 13.0 1.0 CA B:GLU86 3.6 14.1 1.0 CG B:GLU86 3.7 24.8 1.0 CB B:LEU41 3.8 9.7 1.0 C B:GLU86 4.0 13.6 1.0 CD2 B:LEU41 4.0 11.2 1.0 CG B:PRO42 4.0 14.2 1.0 CB B:GLU86 4.1 15.3 1.0 CG B:LEU41 4.2 11.3 1.0 CB B:ILE87 4.3 10.0 1.0 CA B:ILE87 4.3 9.1 1.0 O B:GLY85 4.5 15.6 1.0 O B:ILE87 4.5 10.1 1.0 N B:PRO42 4.5 11.0 1.0 CG1 B:ILE87 4.7 9.0 1.0 CA B:LEU41 4.7 8.8 1.0 N B:GLU86 4.9 13.3 1.0 CD B:GLU86 4.9 24.7 1.0 C B:ILE87 4.9 10.7 1.0 C B:LEU41 4.9 10.0 1.0 N B:LEU41 5.0 8.8 1.0

Chlorine binding site 5 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl4 b:20.3 occ:1.00 O B:HOH106 3.1 35.8 1.0 N B:ALA75 3.3 12.4 1.0 CA B:VAL73 3.5 10.4 1.0 O B:HOH182 3.5 28.9 1.0 C B:VAL73 3.5 9.3 1.0 CB B:ALA75 3.6 13.9 1.0 N B:PRO74 3.7 10.4 1.0 CD B:PRO74 3.7 10.5 1.0 CA B:ALA75 3.9 13.3 1.0 O B:VAL73 4.0 9.1 1.0 CB B:VAL73 4.0 10.0 1.0 N B:VAL76 4.1 10.2 1.0 CG2 B:VAL76 4.3 15.7 1.0 C B:ALA75 4.3 13.6 1.0 CG1 B:VAL73 4.3 10.6 1.0 O B:SER72 4.4 10.8 1.0 C B:PRO74 4.4 11.1 1.0 CG B:PRO74 4.5 11.1 1.0 CA B:PRO74 4.6 10.7 1.0 N B:VAL73 4.7 10.0 1.0

Chlorine binding site 6 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl5 b:14.2 occ:1.00 O B:HOH146 3.1 25.8 1.0 O B:HOH6 3.1 7.9 0.3 C B:PRO57 3.2 9.0 1.0 N B:GLN60 3.3 11.8 1.0 N B:LYS59 3.3 8.0 1.0 CA B:PRO57 3.3 9.8 1.0 CB B:LYS59 3.5 11.3 1.0 O B:PRO57 3.6 10.6 1.0 CG B:GLN60 3.7 11.0 1.0 N B:PHE58 3.7 10.3 1.0 CA B:LYS59 3.8 11.8 1.0 CB B:PRO57 3.8 8.8 1.0 C B:LYS59 4.0 12.5 1.0 CB B:GLN60 4.1 14.2 1.0 CG B:LYS59 4.1 14.1 1.0 C B:PHE58 4.2 8.7 1.0 CA B:GLN60 4.3 11.2 1.0 CD B:GLN60 4.4 16.6 1.0 CA B:PHE58 4.5 9.2 1.0 N B:PRO57 4.7 9.4 1.0 O B:ILE56 4.7 10.1 1.0 OE1 B:GLN60 4.7 23.9 1.0

Chlorine binding site 7 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl7 b:26.0 occ:1.00 O B:HOH199 3.0 26.0 1.0 N B:ALA40 3.2 11.3 1.0 O B:HOH168 3.3 25.6 1.0 CD B:ARG43 3.7 15.2 1.0 CA B:VAL39 3.8 11.0 1.0 NE B:ARG43 3.8 22.2 1.0 CB B:ALA40 3.9 12.4 1.0 O B:GLY38 3.9 13.5 1.0 C B:VAL39 4.0 10.7 1.0 O B:HOH159 4.0 38.2 1.0 O B:HOH185 4.1 26.9 1.0 CA B:ALA40 4.2 11.4 1.0 CZ B:ARG43 4.6 32.1 1.0 C B:GLY38 4.7 14.9 1.0 N B:VAL39 4.7 11.7 1.0 CG1 B:VAL39 4.7 11.9 1.0 O B:HOH361 4.7 43.1 1.0 CB B:VAL39 4.8 12.7 1.0 CG B:ARG43 4.8 15.0 1.0 CB B:ARG43 4.9 12.2 1.0

Chlorine binding site 8 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl8 b:33.1 occ:0.33 O B:HOH177 2.9 26.9 1.0 CD B:LYS59 3.7 18.4 1.0 CB B:LYS59 4.0 11.3 1.0 CG B:LYS59 4.0 14.1 1.0 CE B:LYS59 4.2 19.5 1.0 O B:HOH147 4.7 28.6 1.0 NZ B:LYS59 4.8 19.6 1.0 O B:HOH178 4.9 24.9 1.0 O B:HOH6 5.0 7.9 0.3

Chlorine binding site 9 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl9 b:29.0 occ:1.00 O B:HOH192 2.8 47.0 1.0 CL B:CL10 3.1 24.8 1.0 N B:LEU66 3.1 7.8 1.0 CA B:THR65 3.5 10.7 1.0 CB B:THR65 3.7 9.2 1.0 CZ B:PHE58 3.7 11.2 1.0 C B:THR65 3.8 10.4 1.0 CB B:LEU66 3.9 9.7 1.0 O B:HOH179 4.0 18.9 1.0 CA B:LEU66 4.1 8.2 1.0 CE1 B:PHE58 4.2 10.0 1.0 CG2 B:THR65 4.3 10.9 1.0 CE2 B:PHE58 4.4 13.0 1.0 O B:HOH172 4.8 34.8 1.0 O B:PRO64 4.9 12.1 1.0 N B:GLU67 4.9 8.6 1.0 N B:THR65 4.9 10.7 1.0 OG1 B:THR65 4.9 11.3 1.0

Chlorine binding site 10 out of 11 in the Crystal Structure of A Conserved Motif in Human TDRD7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of Crystal Structure of A Conserved Motif in Human TDRD7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl10 b:24.8 occ:1.00 O B:HOH153 2.7 21.2 1.0 O B:HOH179 2.9 18.9 1.0 N B:GLU67 3.0 8.6 1.0 CL B:CL9 3.1 29.0 1.0 N B:LEU66 3.5 7.8 1.0 CB B:GLU67 3.5 8.1 1.0 CB B:THR65 3.7 9.2 1.0 CB B:LEU66 3.7 9.7 1.0 O B:HOH172 3.8 34.8 1.0 CA B:GLU67 3.9 8.7 1.0 CA B:LEU66 3.9 8.2 1.0 C B:LEU66 3.9 8.5 1.0 CD2 B:LEU41 4.2 11.2 1.0 OG1 B:THR65 4.2 11.3 1.0 C B:THR65 4.3 10.4 1.0 CA B:THR65 4.5 10.7 1.0 OE1 B:GLU67 4.7 10.7 1.0 CG2 B:THR65 4.7 10.9 1.0 CG B:LEU66 4.8 10.5 1.0 O B:HOH128 4.8 29.8 1.0 CG B:LEU41 5.0 11.3 1.0 CG B:GLU67 5.0 8.3 1.0

C.Xu, A.Dong, J.R.Walker, R.Lam, Y.Guo, C.Bian, Y.Li, C.Bountra, J.Weigelt, C.H.Arrowsmith, A.M.Edwards, J.Min, Structural Genomics Consortium (Sgc). Crystal Structure of A Conserved Motif in Human TDRD7 To Be Published.