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Atomistry » Chlorine » PDB 3s8n-3sei » 3sax » |
Chlorine in PDB 3sax: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}BenzenesulfonamideEnzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}Benzenesulfonamide
All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}Benzenesulfonamide:
4.2.1.1; Protein crystallography data
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}Benzenesulfonamide, PDB code: 3sax
was solved by
S.Grazulis,
E.Manakova,
G.Tamulaitiene,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3sax:
The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}Benzenesulfonamide also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}Benzenesulfonamide
(pdb code 3sax). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}Benzenesulfonamide, PDB code: 3sax: Chlorine binding site 1 out of 1 in 3saxGo back to Chlorine Binding Sites List in 3sax
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 2- Chloro-5-{[(5-Ethyl-2-Pyrimidinyl)Sulfanyl]Acetyl}Benzenesulfonamide
Mono view Stereo pair view
Reference:
E.Capkauskaite,
A.Zubriene,
L.Baranauskiene,
G.Tamulaitiene,
E.Manakova,
V.Kairys,
S.Grazulis,
S.Tumkevicius,
D.Matulis.
Design of [(2-Pyrimidinylthio)Acetyl]Benzenesulfonamides As Inhibitors of Human Carbonic Anhydrases. Eur.J.Med.Chem. V. 51 259 2012.
Page generated: Sat Dec 12 10:08:59 2020
ISSN: ISSN 0223-5234 PubMed: 22440859 DOI: 10.1016/J.EJMECH.2012.02.050 |
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