Chlorine in PDB 3sg9: Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type Iva Kanamycin A Complex

The structure of Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type Iva Kanamycin A Complex, PDB code: 3sg9 was solved by K.Shi, D.R.Houston, A.M.Berghuis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.15
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.903, 101.426, 73.399, 90.00, 100.61, 90.00
R / Rfree (%)	19.5 / 25.1

The binding sites of Chlorine atom in the Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type Iva Kanamycin A Complex (pdb code 3sg9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type Iva Kanamycin A Complex, PDB code: 3sg9:

Chlorine binding site 1 out of 1 in the Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type Iva Kanamycin A Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Aminoglycoside-2''-Phosphotransferase Type Iva Kanamycin A Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl304 b:26.6 occ:1.00 O B:HOH368 3.0 21.1 1.0 N B:ASP19 3.4 25.5 1.0 CA B:TYR17 3.4 20.9 1.0 C B:TYR17 3.4 22.8 1.0 N B:PRO18 3.5 23.7 1.0 CD B:PRO18 3.7 23.9 1.0 CB B:ASP19 3.8 24.3 1.0 CB B:TYR17 4.0 20.5 1.0 O B:TYR17 4.0 22.9 1.0 OD2 B:ASP19 4.0 25.3 1.0 CG B:ASP19 4.1 26.8 1.0 CA B:ASP19 4.1 25.1 1.0 CG B:PRO18 4.2 25.8 1.0 N B:PHE20 4.3 23.6 1.0 CD1 B:TYR17 4.4 19.5 1.0 C B:PRO18 4.4 25.5 1.0 CA B:PRO18 4.5 24.8 1.0 O A:HOH374 4.6 30.9 1.0 N B:TYR17 4.6 19.2 1.0 C B:ASP19 4.6 24.9 1.0 O B:LEU16 4.7 19.2 1.0 CG B:TYR17 4.7 19.6 1.0 O B:HOH369 4.8 25.2 1.0 OD1 B:ASP19 4.9 27.2 1.0 O A:HOH372 5.0 26.8 1.0

K.Shi, D.R.Houston, A.M.Berghuis. Crystal Structures of Antibiotic-Bound Complexes of Aminoglycoside 2''-Phosphotransferase Iva Highlight the Diversity in Substrate Binding Modes Among Aminoglycoside Kinases. Biochemistry V. 50 6237 2011.
ISSN: ISSN 0006-2960
PubMed: 21678960
DOI: 10.1021/BI200747F